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==Crystal structure of cals8 from micromonospora echinospora (P294S mutant)==
==Crystal structure of cals8 from micromonospora echinospora (P294S mutant)==
<StructureSection load='4xrr' size='340' side='right' caption='[[4xrr]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
<StructureSection load='4xrr' size='340' side='right'caption='[[4xrr]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4xrr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_15837 Atcc 15837]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4wb1 4wb1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XRR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XRR FirstGlance]. <br>
<table><tr><td colspan='2'>[[4xrr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Micromonospora_echinospora Micromonospora echinospora]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4wb1 4wb1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XRR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XRR FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">calS8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1877 ATCC 15837])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xrr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xrr OCA], [https://pdbe.org/4xrr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xrr RCSB], [https://www.ebi.ac.uk/pdbsum/4xrr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xrr ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xrr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xrr OCA], [http://pdbe.org/4xrr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xrr RCSB], [http://www.ebi.ac.uk/pdbsum/4xrr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4xrr ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8KNF6_MICEC Q8KNF6_MICEC]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 15837]]
[[Category: Large Structures]]
[[Category: Babnigg, G]]
[[Category: Micromonospora echinospora]]
[[Category: Bigelow, L]]
[[Category: Babnigg G]]
[[Category: Bingman, C A]]
[[Category: Bigelow L]]
[[Category: Endres, M]]
[[Category: Bingman CA]]
[[Category: Joachimiak, A]]
[[Category: Endres M]]
[[Category: Kharel, M K]]
[[Category: Joachimiak A]]
[[Category: Structural genomic]]
[[Category: Kharel MK]]
[[Category: Michalska, K]]
[[Category: Michalska K]]
[[Category: NatPro, Enzyme Discovery for Natural Product Biosynthesis]]
[[Category: Phillips Jr GN]]
[[Category: Phillips, G N]]
[[Category: Singh S]]
[[Category: Singh, S]]
[[Category: Thorson JS]]
[[Category: Thorson, J S]]
[[Category: Yennamalli RM]]
[[Category: Yennamalli, R M]]
[[Category: Calicheamicin]]
[[Category: Enzyme discovery for natural product biosynthesis]]
[[Category: Mcsg]]
[[Category: Natpro]]
[[Category: Oxidoreductase]]
[[Category: Psi-biology]]