3raj: Difference between revisions
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==Crystal structure of human CD38 in complex with the Fab fragment of antibody HB7== | ==Crystal structure of human CD38 in complex with the Fab fragment of antibody HB7== | ||
<StructureSection load='3raj' size='340' side='right' caption='[[3raj]], [[Resolution|resolution]] 3.04Å' scene=''> | <StructureSection load='3raj' size='340' side='right'caption='[[3raj]], [[Resolution|resolution]] 3.04Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3raj]] is a 3 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3raj]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RAJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RAJ FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.044Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3raj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3raj OCA], [https://pdbe.org/3raj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3raj RCSB], [https://www.ebi.ac.uk/pdbsum/3raj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3raj ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/CD38_HUMAN CD38_HUMAN] Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. | ||
==See Also== | ==See Also== | ||
*[[3D structures of antibody|3D structures of antibody]] | *[[Antibody 3D structures|Antibody 3D structures]] | ||
*[[Cluster of Differentiation CD38|Cluster of Differentiation CD38]] | |||
*[[3D structures of non-human antibody|3D structures of non-human antibody]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mus musculus]] | ||
[[Category: | [[Category: Hao Q]] | ||
[[Category: | [[Category: Lee HC]] | ||
[[Category: | [[Category: Zhang H]] | ||
Latest revision as of 17:15, 1 November 2023
Crystal structure of human CD38 in complex with the Fab fragment of antibody HB7
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