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==1.63 Angstrom resolution crystal structure of dTDP-4-dehydrorhamnose 3,5-epimerase (rfbC) from Bacillus anthracis str. Ames with TDP and PPi bound==
==1.63 Angstrom resolution crystal structure of dTDP-4-dehydrorhamnose 3,5-epimerase (rfbC) from Bacillus anthracis str. Ames with TDP and PPi bound==
<StructureSection load='3ryk' size='340' side='right' caption='[[3ryk]], [[Resolution|resolution]] 1.63&Aring;' scene=''>
<StructureSection load='3ryk' size='340' side='right'caption='[[3ryk]], [[Resolution|resolution]] 1.63&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3ryk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis_(strain_ames) Bacillus anthracis (strain ames)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RYK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RYK FirstGlance]. <br>
<table><tr><td colspan='2'>[[3ryk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis_str._Ames Bacillus anthracis str. Ames]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RYK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RYK FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=TYD:THYMIDINE-5-DIPHOSPHATE'>TYD</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.631&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAS1136, BA_1229, GBAA_1229, rfbC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=198094 Bacillus anthracis (strain Ames)])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=TYD:THYMIDINE-5-DIPHOSPHATE'>TYD</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dTDP-4-dehydrorhamnose_3,5-epimerase dTDP-4-dehydrorhamnose 3,5-epimerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.3.13 5.1.3.13] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ryk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ryk OCA], [https://pdbe.org/3ryk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ryk RCSB], [https://www.ebi.ac.uk/pdbsum/3ryk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ryk ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ryk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ryk OCA], [http://pdbe.org/3ryk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ryk RCSB], [http://www.ebi.ac.uk/pdbsum/3ryk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ryk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A6L7H6N0_BACAN A0A6L7H6N0_BACAN] Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.[RuleBase:RU364069]
==See Also==
*[[RmlC|RmlC]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: DTDP-4-dehydrorhamnose 3,5-epimerase]]
[[Category: Bacillus anthracis str. Ames]]
[[Category: Anderson, W F]]
[[Category: Large Structures]]
[[Category: Structural genomic]]
[[Category: Anderson WF]]
[[Category: Halavaty, A S]]
[[Category: Halavaty AS]]
[[Category: Kuhn, M]]
[[Category: Kuhn M]]
[[Category: Kwon, K]]
[[Category: Kwon K]]
[[Category: Minasov, G]]
[[Category: Minasov G]]
[[Category: Shuvalova, L]]
[[Category: Shuvalova L]]
[[Category: 5-epimerase]]
[[Category: Dtdp-4-dehydrorhamnose 3]]
[[Category: Infectious disease]]
[[Category: Isomerase]]
[[Category: Jelly roll-like topology]]
[[Category: Rhamnose pathway]]
[[Category: The 3 and 5 positions of the sugar ring]]
[[Category: The enzyme epimerizes at two carbon center]]
Retrieved from "https://proteopedia.org/3ryk"