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==APO Form of carbon disulfide hydrolase (selenomethionine form)==
==APO Form of carbon disulfide hydrolase (selenomethionine form)==
<StructureSection load='3teo' size='340' side='right' caption='[[3teo]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='3teo' size='340' side='right'caption='[[3teo]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3teo]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Acis1 Acis1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TEO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TEO FirstGlance]. <br>
<table><tr><td colspan='2'>[[3teo]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Acidianus_sp._A1-3 Acidianus sp. A1-3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TEO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TEO FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PE3:3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL'>PE3</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PE3:3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL'>PE3</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ten|3ten]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3teo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3teo OCA], [https://pdbe.org/3teo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3teo RCSB], [https://www.ebi.ac.uk/pdbsum/3teo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3teo ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cs2 hydrolase ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1071056 ACIS1])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3teo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3teo OCA], [http://pdbe.org/3teo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3teo RCSB], [http://www.ebi.ac.uk/pdbsum/3teo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3teo ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CS2H_ACIS1 CS2H_ACIS1] Catalyzes the conversion of carbon disulfide into hydrogen sulfide and carbon dioxide, with carbonyl sulfide as an intermediate. Likely plays a key role in sulfur metabolism that allows Acidianus sp. A1-3 to grow on carbon disulfide as the main carbon and energy source. Does not show carbonic anhydrase activity (hydration of CO(2) to carbonate).<ref>PMID:22012399</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Acis1]]
[[Category: Acidianus sp. A1-3]]
[[Category: Barends, T R.M B]]
[[Category: Large Structures]]
[[Category: Camp, H J.M Op den]]
[[Category: Barends TRMB]]
[[Category: Hermans, J]]
[[Category: Hermans J]]
[[Category: Heuvel, L P.van den]]
[[Category: Jetten MSM]]
[[Category: Jetten, M S.M]]
[[Category: Khadem A]]
[[Category: Khadem, A]]
[[Category: Menzel A]]
[[Category: Menzel, A]]
[[Category: Op den Camp HJM]]
[[Category: Pol, A]]
[[Category: Pol A]]
[[Category: Russ, L]]
[[Category: Russ L]]
[[Category: Scherer, A]]
[[Category: Scherer A]]
[[Category: Schlichting, I]]
[[Category: Schlichting I]]
[[Category: Shoeman, R L]]
[[Category: Shoeman RL]]
[[Category: Smeulders, M J]]
[[Category: Smeulders MJ]]
[[Category: Udvarhelyi, A]]
[[Category: Udvarhelyi A]]
[[Category: Wessels, H J.C T]]
[[Category: Wessels HJCT]]
[[Category: Zandvoort, M H]]
[[Category: Zandvoort MH]]
[[Category: Beta carbonic anhydrase fold]]
[[Category: Van den Heuvel LP]]
[[Category: Carbon disulfide hydrolysis]]
[[Category: Hydrolase]]
Retrieved from "https://proteopedia.org/3teo"