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==Contribution of disulfide bond toward thermostability in hyperthermostable endocellulase==
==Contribution of disulfide bond toward thermostability in hyperthermostable endocellulase==
<StructureSection load='4dm1' size='340' side='right' caption='[[4dm1]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
<StructureSection load='4dm1' size='340' side='right'caption='[[4dm1]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4dm1]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DM1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DM1 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4dm1]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DM1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DM1 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2zun|2zun]], [[3axx|3axx]], [[3qhn|3qhn]], [[3qhm|3qhm]], [[3qho|3qho]], [[4dm2|4dm2]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PH1171 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=70601 Pyrococcus horikoshii])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dm1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dm1 OCA], [https://pdbe.org/4dm1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dm1 RCSB], [https://www.ebi.ac.uk/pdbsum/4dm1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dm1 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dm1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dm1 OCA], [http://pdbe.org/4dm1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4dm1 RCSB], [http://www.ebi.ac.uk/pdbsum/4dm1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4dm1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/O58925_PYRHO O58925_PYRHO]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Cellulase]]
[[Category: Large Structures]]
[[Category: Pyrococcus horikoshii]]
[[Category: Pyrococcus horikoshii OT3]]
[[Category: Ishikawa, K]]
[[Category: Ishikawa K]]
[[Category: Kim, H W]]
[[Category: Kim H-W]]
[[Category: Disulfide bond]]
[[Category: Glycosyl hydrolase]]
[[Category: Hydrolase]]
[[Category: Hydrolizaiton]]
[[Category: Hyperthermophilic]]
[[Category: Membrane-bound]]
[[Category: Tim barrel]]

Latest revision as of 09:56, 30 October 2024

Contribution of disulfide bond toward thermostability in hyperthermostable endocellulase

4dm1, resolution 1.75Å

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