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==Crystal structure of Streptomyces caespitosus sermetstatin in complex with Bacillus licheniformis subtilisin==
==Crystal structure of Streptomyces caespitosus sermetstatin in complex with Bacillus licheniformis subtilisin==
<StructureSection load='4hx2' size='340' side='right' caption='[[4hx2]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
<StructureSection load='4hx2' size='340' side='right'caption='[[4hx2]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4hx2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"streptomyces_caespitosus"_sugawara_and_hata "streptomyces caespitosus" sugawara and hata] and [http://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HX2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HX2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4hx2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis] and [https://en.wikipedia.org/wiki/Streptomyces_caespitosus Streptomyces caespitosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HX2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HX2 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1AX:(2R,2R)-3,3-OXYDIPROPANE-1,2-DIOL'>1AX</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4hwx|4hwx]], [[4hx3|4hx3]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1AX:(2R,2R)-3,3-OXYDIPROPANE-1,2-DIOL'>1AX</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ScNPI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=53502 "Streptomyces caespitosus" Sugawara and Hata])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hx2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hx2 OCA], [https://pdbe.org/4hx2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hx2 RCSB], [https://www.ebi.ac.uk/pdbsum/4hx2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hx2 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Subtilisin Subtilisin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.62 3.4.21.62] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hx2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hx2 OCA], [http://pdbe.org/4hx2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hx2 RCSB], [http://www.ebi.ac.uk/pdbsum/4hx2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hx2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9FDF2_BACLI Q9FDF2_BACLI]
==See Also==
*[[Subtilisin 3D structures|Subtilisin 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Streptomyces caespitosus sugawara and hata]]
[[Category: Bacillus licheniformis]]
[[Category: Bacillus licheniformis]]
[[Category: Subtilisin]]
[[Category: Large Structures]]
[[Category: Arolas, J L]]
[[Category: Streptomyces caespitosus]]
[[Category: Gomis-Ruth, F X]]
[[Category: Arolas JL]]
[[Category: Martinez-Rodriguez, S]]
[[Category: Gomis-Ruth FX]]
[[Category: Trillo-Muyo, S]]
[[Category: Martinez-Rodriguez S]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Trillo-Muyo S]]
[[Category: Streptomyces subtilisin inhibitor fold]]
[[Category: Subtilisin carlsberg]]

Latest revision as of 15:12, 20 September 2023

Crystal structure of Streptomyces caespitosus sermetstatin in complex with Bacillus licheniformis subtilisin

4hx2, resolution 2.25Å

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