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==Crystal Structure of Apo Human Epidermal Fatty Acid Binding Protein (FABP5)==
==Crystal Structure of Apo Human Epidermal Fatty Acid Binding Protein (FABP5)==
<StructureSection load='4lkp' size='340' side='right' caption='[[4lkp]], [[Resolution|resolution]] 1.67&Aring;' scene=''>
<StructureSection load='4lkp' size='340' side='right'caption='[[4lkp]], [[Resolution|resolution]] 1.67&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4lkp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LKP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LKP FirstGlance]. <br>
<table><tr><td colspan='2'>[[4lkp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LKP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LKP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.67&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4lkt|4lkt]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FABP5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lkp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lkp OCA], [https://pdbe.org/4lkp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lkp RCSB], [https://www.ebi.ac.uk/pdbsum/4lkp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lkp ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lkp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lkp OCA], [http://pdbe.org/4lkp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lkp RCSB], [http://www.ebi.ac.uk/pdbsum/4lkp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lkp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FABP5_HUMAN FABP5_HUMAN]] High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation.  
[https://www.uniprot.org/uniprot/FABP5_HUMAN FABP5_HUMAN] High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4lkp" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4lkp" style="background-color:#fffaf0;"></div>
==See Also==
*[[Fatty acid-binding protein 3D structures|Fatty acid-binding protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Armstrong, E H]]
[[Category: Large Structures]]
[[Category: Ortlund, E A]]
[[Category: Armstrong EH]]
[[Category: Beta barrel]]
[[Category: Ortlund EA]]
[[Category: Beta clam]]
[[Category: Fatty acid binding protein]]
[[Category: Fatty acid]]
[[Category: Lipid binding protein]]
[[Category: Nucleus]]