4mif: Difference between revisions

<StructureSection load='4mif' size='340' side='right'caption='[[4mif]], [[Resolution|resolution]] 1.80&Aring;' scene=''>

<table><tr><td colspan='2'>[[4mif]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Phanerodontia_chrysosporium Phanerodontia chrysosporium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MIF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MIF FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FDA:DIHYDROFLAVINE-ADENINE+DINUCLEOTIDE'>FDA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mif FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mif OCA], [https://pdbe.org/4mif PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mif RCSB], [https://www.ebi.ac.uk/pdbsum/4mif PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mif ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/P2OX_PHACH P2OX_PHACH] Catalyzes the oxidation of various aldopyranoses and disaccharides on carbon-2 to the corresponding 2-keto sugars concomitant with the reduction of O(2) to H(2)O(2). Plays an important role in lignin degradation of wood rot fungi by supplying the essential cosubstrate H(2)O(2) for the ligninolytic peroxidases, lignin peroxidase and manganese-dependent peroxidase. The preferred substrate is D-glucose which is converted to 2-dehydro-D-glucose, an intermediate of a secondary metabolic pathway leading to the antibiotic cortalcerone. Acts also on D-xylose, together with D-glucose the major sugars derived from wood, on L-sorbose, D-galactose and 1,5-anhydroglucitol, a diagnostic marker of diabetes mellitus.<ref>PMID:9210340</ref> <ref>PMID:8661938</ref>  

[[Category: Large Structures]]

[[Category: Phanerodontia chrysosporium]]

[[Category: Divne C]]

[[Category: Fusco L]]

[[Category: Haltrich D]]

[[Category: Hassan N]]

[[Category: Peterbauer C]]

[[Category: Pisanelli I]]

[[Category: Spadiut O]]

[[Category: Tan TC]]