4x2q: Difference between revisions
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==Crystal Structure of Human Aldehyde Dehydrogenase, ALDH1a2== | ==Crystal Structure of Human Aldehyde Dehydrogenase, ALDH1a2== | ||
<StructureSection load='4x2q' size='340' side='right' caption='[[4x2q]], [[Resolution|resolution]] 2.94Å' scene=''> | <StructureSection load='4x2q' size='340' side='right'caption='[[4x2q]], [[Resolution|resolution]] 2.94Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4x2q]] is a 4 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4x2q]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X2Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X2Q FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.94Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> | |||
<tr id=' | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x2q OCA], [https://pdbe.org/4x2q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x2q RCSB], [https://www.ebi.ac.uk/pdbsum/4x2q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x2q ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/AL1A2_HUMAN AL1A2_HUMAN] Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Does metabolize octanal and decanal but does not metabolize citral, benzaldehyde, acetaldehyde and propanal efficiently (By similarity). | ||
==See Also== | |||
*[[Aldehyde dehydrogenase 3D structures|Aldehyde dehydrogenase 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Amory | [[Category: Amory JK]] | ||
[[Category: Goldstein | [[Category: Goldstein AS]] | ||
[[Category: Le Trong I]] | |||
[[Category: Paik J]] | |||
[[Category: Trong | [[Category: Stenkamp RE]] | ||
[[Category: | |||
[[Category: | |||
Latest revision as of 07:40, 27 September 2023
Crystal Structure of Human Aldehyde Dehydrogenase, ALDH1a2
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