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[[Image:2aq2.gif|left|200px]]


{{Structure
==Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutant==
|PDB= 2aq2 |SIZE=350|CAPTION= <scene name='initialview01'>2aq2</scene>, resolution 1.800&Aring;
<StructureSection load='2aq2' size='340' side='right'caption='[[2aq2]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
<table><tr><td colspan='2'>[[2aq2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AQ2 FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
|GENE= entC3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2aq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aq2 OCA], [https://pdbe.org/2aq2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2aq2 RCSB], [https://www.ebi.ac.uk/pdbsum/2aq2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2aq2 ProSAT]</span></td></tr>
|RELATEDENTRY=[[2apb|2APB]], [[2apf|2APF]], [[2apt|2APT]], [[2apv|2APV]], [[2apw|2APW]], [[2apx|2APX]], [[2aq1|2AQ1]], [[2aq3|2AQ3]]
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aq2 OCA], [http://www.ebi.ac.uk/pdbsum/2aq2 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2aq2 RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/TVB5_MOUSE TVB5_MOUSE]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aq/2aq2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2aq2 ConSurf].
<div style="clear:both"></div>


'''Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutant'''
==See Also==
 
*[[T-cell receptor 3D structures|T-cell receptor 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2AQ2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQ2 OCA].
[[Category: Large Structures]]
 
==Reference==
The nitty-gritty of protein interactions., Schreiber G, Structure. 2005 Dec;13(12):1737-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16338399 16338399]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Single protein]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
[[Category: Cho, S.]]
[[Category: Cho S]]
[[Category: Guan, R.]]
[[Category: Guan R]]
[[Category: Kerzic, M C.]]
[[Category: Kerzic MC]]
[[Category: Kieke, M C.]]
[[Category: Kieke MC]]
[[Category: Kranz, D M.]]
[[Category: Kranz DM]]
[[Category: Mariuzza, R A.]]
[[Category: Mariuzza RA]]
[[Category: Sundberg, E J.]]
[[Category: Sundberg EJ]]
[[Category: Swaminathan, C P.]]
[[Category: Swaminathan CP]]
[[Category: Yang, J.]]
[[Category: Yang J]]
[[Category: complex structure]]
[[Category: staphlococcal enterotoxin c3]]
[[Category: t-cell receptor v beta domain]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:55:47 2008''

Latest revision as of 00:47, 21 November 2024

Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutant

2aq2, resolution 1.80Å

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