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[[Image:2aqs.jpg|left|200px]]


{{Structure
==CU/ZN superoxide dismutase from neisseria meningitidis K91E, K94E double mutant==
|PDB= 2aqs |SIZE=350|CAPTION= <scene name='initialview01'>2aqs</scene>, resolution 1.70&Aring;
<StructureSection load='2aqs' size='340' side='right'caption='[[2aqs]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=CU1:COPPER+(I)+ION'>CU1</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
<table><tr><td colspan='2'>[[2aqs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_meningitidis Neisseria meningitidis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AQS FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
|GENE= sodC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=487 Neisseria meningitidis])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=CU1:COPPER+(I)+ION'>CU1</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2aqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aqs OCA], [https://pdbe.org/2aqs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2aqs RCSB], [https://www.ebi.ac.uk/pdbsum/2aqs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2aqs ProSAT]</span></td></tr>
|RELATEDENTRY=[[2aqm|2AQM]], [[2aqn|2AQN]], [[2aqp|2AQP]], [[2aqq|2AQQ]], [[2aqr|2AQR]], [[2aqt|2AQT]]
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aqs OCA], [http://www.ebi.ac.uk/pdbsum/2aqs PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2aqs RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/SODC_NEIMB SODC_NEIMB] Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aq/2aqs_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2aqs ConSurf].
<div style="clear:both"></div>


'''CU/ZN superoxide dismutase from neisseria meningitidis K91E, K94E double mutant'''
==See Also==
 
*[[Superoxide dismutase 3D structures|Superoxide dismutase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2AQS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Neisseria_meningitidis Neisseria meningitidis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQS OCA].
[[Category: Large Structures]]
[[Category: Neisseria meningitidis]]
[[Category: Neisseria meningitidis]]
[[Category: Single protein]]
[[Category: Bruns CK]]
[[Category: Superoxide dismutase]]
[[Category: Cabelli DE]]
[[Category: Bruns, C K.]]
[[Category: Cao Z]]
[[Category: Cabelli, D E.]]
[[Category: DiDonato M]]
[[Category: Cao, Z.]]
[[Category: Getzoff ED]]
[[Category: DiDonato, M.]]
[[Category: Kassmann CJ]]
[[Category: Getzoff, E D.]]
[[Category: Kroll JS]]
[[Category: Kassmann, C J.]]
[[Category: Tabatabai LB]]
[[Category: Kroll, J S.]]
[[Category: Tabatabai, L B.]]
[[Category: cu/zn superoxide dismutase]]
[[Category: electrostatic guidance]]
[[Category: neisseria meningitidi]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:56:03 2008''
Retrieved from "https://proteopedia.org/2aqs"