1e6m: Difference between revisions

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==TWO-COMPONENT SIGNAL TRANSDUCTION SYSTEM D57A MUTANT OF CHEY==
==TWO-COMPONENT SIGNAL TRANSDUCTION SYSTEM D57A MUTANT OF CHEY==
<StructureSection load='1e6m' size='340' side='right' caption='[[1e6m]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='1e6m' size='340' side='right'caption='[[1e6m]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1e6m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E6M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1E6M FirstGlance]. <br>
<table><tr><td colspan='2'>[[1e6m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E6M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E6M FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1udr|1udr]], [[1eay|1eay]], [[1c4w|1c4w]], [[1bdj|1bdj]], [[1ab5|1ab5]], [[1ab6|1ab6]], [[1a0o|1a0o]], [[1e6k|1e6k]], [[1e6l|1e6l]], [[3chy|3chy]], [[5chy|5chy]], [[6chy|6chy]], [[1chn|1chn]], [[1cey|1cey]], [[1ymu|1ymu]], [[1ymv|1ymv]], [[1cye|1cye]], [[1vlz|1vlz]], [[1ehc|1ehc]], [[1hey|1hey]], [[1d4z|1d4z]], [[1djm|1djm]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1e6m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e6m OCA], [http://pdbe.org/1e6m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1e6m RCSB], [http://www.ebi.ac.uk/pdbsum/1e6m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1e6m ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e6m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e6m OCA], [https://pdbe.org/1e6m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e6m RCSB], [https://www.ebi.ac.uk/pdbsum/1e6m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e6m ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CHEY_ECOLI CHEY_ECOLI]] Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. In its active (phosphorylated or acetylated) form, CheY exhibits enhanced binding to a switch component, FliM, at the flagellar motor which induces a change from counterclockwise to clockwise flagellar rotation. Overexpression of CheY in association with MotA and MotB improves motility of a ycgR disruption, suggesting there is an interaction (direct or indirect) between the c-di-GMP-binding flagellar brake protein and the flagellar stator.<ref>PMID:20346719</ref>
[https://www.uniprot.org/uniprot/CHEY_ECOLI CHEY_ECOLI] Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. In its active (phosphorylated or acetylated) form, CheY exhibits enhanced binding to a switch component, FliM, at the flagellar motor which induces a change from counterclockwise to clockwise flagellar rotation. Overexpression of CheY in association with MotA and MotB improves motility of a ycgR disruption, suggesting there is an interaction (direct or indirect) between the c-di-GMP-binding flagellar brake protein and the flagellar stator.<ref>PMID:20346719</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e6/1e6m_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e6/1e6m_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 1e6m" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1e6m" style="background-color:#fffaf0;"></div>
==See Also==
*[[Chemotaxis protein|Chemotaxis protein]]
*[[Chemotaxis protein 3D structures|Chemotaxis protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: Coll, M]]
[[Category: Large Structures]]
[[Category: Cronet, P]]
[[Category: Coll M]]
[[Category: Lacroix, E]]
[[Category: Cronet P]]
[[Category: Lopez-Hernandez, E]]
[[Category: Lacroix E]]
[[Category: Parraga, A]]
[[Category: Lopez-Hernandez E]]
[[Category: Serrano, L]]
[[Category: Parraga A]]
[[Category: Sola, M]]
[[Category: Serrano L]]
[[Category: Active site mutant]]
[[Category: Sola M]]
[[Category: Chemotaxis]]
[[Category: Signaling protein]]
[[Category: Two-component signal transduction system]]
Retrieved from "https://proteopedia.org/1e6m"