5nzy: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
No edit summary
 
Line 1: Line 1:


==Crystal structure of DNA cross-link repair protein 1A in complex with Cefotaxime==
==Crystal structure of DNA cross-link repair protein 1A in complex with Cefotaxime==
<StructureSection load='5nzy' size='340' side='right' caption='[[5nzy]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
<StructureSection load='5nzy' size='340' side='right'caption='[[5nzy]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5nzy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NZY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NZY FirstGlance]. <br>
<table><tr><td colspan='2'>[[5nzy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NZY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NZY FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CE3:(6R,7R)-3-(ACETYLOXYMETHYL)-7-[[(2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-METHOXYIMINO-ETHANOYL]AMINO]-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC+ACID'>CE3</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.551&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DCLRE1A, KIAA0086, SNM1, SNM1A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CE3:(6R,7R)-3-(ACETYLOXYMETHYL)-7-[[(2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-METHOXYIMINO-ETHANOYL]AMINO]-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC+ACID'>CE3</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nzy OCA], [http://pdbe.org/5nzy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nzy RCSB], [http://www.ebi.ac.uk/pdbsum/5nzy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nzy ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5nzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nzy OCA], [https://pdbe.org/5nzy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5nzy RCSB], [https://www.ebi.ac.uk/pdbsum/5nzy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5nzy ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DCR1A_HUMAN DCR1A_HUMAN]] May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons.<ref>PMID:15542852</ref>
[https://www.uniprot.org/uniprot/DCR1A_HUMAN DCR1A_HUMAN] May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons.<ref>PMID:15542852</ref>  
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Aitkenhead, H]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C H]]
[[Category: Aitkenhead H]]
[[Category: Bountra, C]]
[[Category: Arrowsmith CH]]
[[Category: Burgess-Brown, N A]]
[[Category: Bountra C]]
[[Category: Delft, F von]]
[[Category: Burgess-Brown NA]]
[[Category: Edwards, A]]
[[Category: Edwards A]]
[[Category: Gileadi, O]]
[[Category: Gileadi O]]
[[Category: Krojer, T]]
[[Category: Krojer T]]
[[Category: Kupinska, K]]
[[Category: Kupinska K]]
[[Category: Newman, J A]]
[[Category: Newman JA]]
[[Category: Talon, R]]
[[Category: Talon R]]
[[Category: Cephalosporin]]
[[Category: Von Delft F]]
[[Category: Cross-link repair]]
[[Category: Dclre1a]]
[[Category: Dna binding protein]]
[[Category: Exonulcease]]
Retrieved from "https://proteopedia.org/5nzy"