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==SAD structure of Thermolysin obtained by multi crystal data collection==
==SAD structure of Thermolysin obtained by multi crystal data collection==
<StructureSection load='5a3y' size='340' side='right' caption='[[5a3y]], [[Resolution|resolution]] 1.27&Aring;' scene=''>
<StructureSection load='5a3y' size='340' side='right'caption='[[5a3y]], [[Resolution|resolution]] 1.27&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5a3y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A3Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A3Y FirstGlance]. <br>
<table><tr><td colspan='2'>[[5a3y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A3Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5A3Y FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene>, <scene name='pdbligand=TMO:TRIMETHYLAMINE+OXIDE'>TMO</scene>, <scene name='pdbligand=VAL:VALINE'>VAL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.27&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5a3z|5a3z]], [[5a44|5a44]], [[5a45|5a45]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene>, <scene name='pdbligand=TMO:TRIMETHYLAMINE+OXIDE'>TMO</scene>, <scene name='pdbligand=VAL:VALINE'>VAL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5a3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a3y OCA], [https://pdbe.org/5a3y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5a3y RCSB], [https://www.ebi.ac.uk/pdbsum/5a3y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5a3y ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a3y OCA], [http://pdbe.org/5a3y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5a3y RCSB], [http://www.ebi.ac.uk/pdbsum/5a3y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5a3y ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/THER_BACTH THER_BACTH]] Extracellular zinc metalloprotease.  
[https://www.uniprot.org/uniprot/THER_BACTH THER_BACTH] Extracellular zinc metalloprotease.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Thermolysin|Thermolysin]]
*[[Thermolysin 3D structures|Thermolysin 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Bacillus thermoproteolyticus]]
[[Category: Bacillus thermoproteolyticus]]
[[Category: Thermolysin]]
[[Category: Large Structures]]
[[Category: Bourenkov, G]]
[[Category: Bourenkov G]]
[[Category: Gordeliy, V I]]
[[Category: Gordeliy VI]]
[[Category: Leonard, G A]]
[[Category: Leonard GA]]
[[Category: McCarthy, A A]]
[[Category: McCarthy AA]]
[[Category: Mueller-Dieckmann, C]]
[[Category: Mueller-Dieckmann C]]
[[Category: Popov, A N]]
[[Category: Popov AN]]
[[Category: Round, E S]]
[[Category: Round ES]]
[[Category: Sanctis, D de]]
[[Category: Svensson O]]
[[Category: Svensson, O]]
[[Category: Zander U]]
[[Category: Zander, U]]
[[Category: De Sanctis D]]
[[Category: Hydrolase]]
[[Category: Multi crystal data collection]]
[[Category: Sad]]
[[Category: Ssx]]
[[Category: Synchrotron serial crystallography]]

Latest revision as of 11:36, 9 May 2024

SAD structure of Thermolysin obtained by multi crystal data collection

5a3y, resolution 1.27Å

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