2b7g: Difference between revisions
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==Structure of the Smaug Recognition RNA Element== | |||
<StructureSection load='2b7g' size='340' side='right'caption='[[2b7g]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2b7g]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B7G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B7G FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b7g OCA], [https://pdbe.org/2b7g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b7g RCSB], [https://www.ebi.ac.uk/pdbsum/2b7g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b7g ProSAT]</span></td></tr> | |||
</table> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
== | |||
The putative yeast post-transcriptional regulator Vts1p and its related protein Smaug, from Drosophila melanogaster, each use a sterile alpha motif (SAM) domain to bind an RNA hairpin termed the Smaug recognition element (SRE). Here, we present the NMR structures of the Vts1p-SRE complex and the free SRE. Structural highlights include the direct recognition of a guanine base and the formation or stabilization of a base pair in the SRE loop. | The putative yeast post-transcriptional regulator Vts1p and its related protein Smaug, from Drosophila melanogaster, each use a sterile alpha motif (SAM) domain to bind an RNA hairpin termed the Smaug recognition element (SRE). Here, we present the NMR structures of the Vts1p-SRE complex and the free SRE. Structural highlights include the direct recognition of a guanine base and the formation or stabilization of a base pair in the SRE loop. | ||
RNA recognition by the Vts1p SAM domain.,Johnson PE, Donaldson LW Nat Struct Mol Biol. 2006 Feb;13(2):177-8. Epub 2006 Jan 22. PMID:16429155<ref>PMID:16429155</ref> | |||
RNA recognition by the Vts1p SAM domain., Johnson PE, Donaldson LW | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
<div class="pdbe-citations 2b7g" style="background-color:#fffaf0;"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Donaldson LW]] | |||
[[Category: Johnson PE]] | |||
Latest revision as of 16:33, 13 December 2023
Structure of the Smaug Recognition RNA Element
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