4ytk: Difference between revisions
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==Structure of the KOW1-Linker1 domain of Transcription Elongation Factor Spt5== | ==Structure of the KOW1-Linker1 domain of Transcription Elongation Factor Spt5== | ||
<StructureSection load='4ytk' size='340' side='right' caption='[[4ytk]], [[Resolution|resolution]] 1.09Å' scene=''> | <StructureSection load='4ytk' size='340' side='right'caption='[[4ytk]], [[Resolution|resolution]] 1.09Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4ytk]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4ytk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YTK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YTK FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.0904Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ytk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ytk OCA], [https://pdbe.org/4ytk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ytk RCSB], [https://www.ebi.ac.uk/pdbsum/4ytk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ytk ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/SPT5_YEAST SPT5_YEAST] The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.<ref>PMID:12554661</ref> <ref>PMID:12556496</ref> <ref>PMID:15780939</ref> <ref>PMID:16172632</ref> <ref>PMID:9450930</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 18: | Line 18: | ||
</div> | </div> | ||
<div class="pdbe-citations 4ytk" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4ytk" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Elongation factor 3D structures|Elongation factor 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Fu | [[Category: Saccharomyces cerevisiae S288C]] | ||
[[Category: Hartzog | [[Category: Fu J]] | ||
[[Category: Li | [[Category: Hartzog GA]] | ||
[[Category: Meyer | [[Category: Li S]] | ||
[[Category: Takagi | [[Category: Meyer PA]] | ||
[[Category: Yamada | [[Category: Takagi Y]] | ||
[[Category: Zhang | [[Category: Yamada K]] | ||
[[Category: Zhang M]] | |||
