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==Crystal structure of Aminopeptidase N in complex with the phosphinic dipeptide analogue LL-(R,S)-2-(pyridin-3-yl)ethylGlyP[CH2]Phe==
==Crystal structure of Aminopeptidase N in complex with the phosphinic dipeptide analogue LL-(R,S)-2-(pyridin-3-yl)ethylGlyP[CH2]Phe==
<StructureSection load='4qir' size='340' side='right' caption='[[4qir]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='4qir' size='340' side='right'caption='[[4qir]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4qir]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Neimb Neimb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QIR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QIR FirstGlance]. <br>
<table><tr><td colspan='2'>[[4qir]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_meningitidis_MC58 Neisseria meningitidis MC58]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QIR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QIR FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=379:3-{[(R)-1-AMINO-3-(PYRIDIN-3-YL)PROPYL](HYDROXY)PHOSPHORYL}-(S)-2-BENZYLPROPANOIC+ACID'>379</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.701&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=379:3-{[(R)-1-AMINO-3-(PYRIDIN-3-YL)PROPYL](HYDROXY)PHOSPHORYL}-(S)-2-BENZYLPROPANOIC+ACID'>379</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pu2|4pu2]], [[4pvb|4pvb]], [[4pw4|4pw4]], [[4qhp|4qhp]], [[4qme|4qme]], [[4qpe|4qpe]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qir FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qir OCA], [https://pdbe.org/4qir PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qir RCSB], [https://www.ebi.ac.uk/pdbsum/4qir PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qir ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pepN, NMB1416 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=122586 NEIMB])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Membrane_alanyl_aminopeptidase Membrane alanyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.2 3.4.11.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qir FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qir OCA], [http://pdbe.org/4qir PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qir RCSB], [http://www.ebi.ac.uk/pdbsum/4qir PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qir ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9JYV4_NEIMB Q9JYV4_NEIMB]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4qir" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4qir" style="background-color:#fffaf0;"></div>
==See Also==
*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Membrane alanyl aminopeptidase]]
[[Category: Large Structures]]
[[Category: Neimb]]
[[Category: Neisseria meningitidis MC58]]
[[Category: Berlicki, L]]
[[Category: Berlicki L]]
[[Category: Joachimiak, A]]
[[Category: Joachimiak A]]
[[Category: Mucha, A]]
[[Category: Mucha A]]
[[Category: Nocek, B]]
[[Category: Nocek B]]
[[Category: Vassiliou, S]]
[[Category: Vassiliou S]]
[[Category: Alanine aminopeptidase]]
[[Category: Aminopeptidase n]]
[[Category: Hydrolase]]
[[Category: M1 family peptidase]]
Retrieved from "https://proteopedia.org/4qir"