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==Crystal structure of BlaC from Mycobacterium tuberculosis bound to phosphate==
==Crystal structure of BlaC from Mycobacterium tuberculosis bound to phosphate==
<StructureSection load='5nj2' size='340' side='right' caption='[[5nj2]], [[Resolution|resolution]] 1.19&Aring;' scene=''>
<StructureSection load='5nj2' size='340' side='right'caption='[[5nj2]], [[Resolution|resolution]] 1.19&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5nj2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NJ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NJ2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5nj2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NJ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NJ2 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=AE4:3,6,9,12,15-PENTAOXAHEPTADECAN-1-OL'>AE4</scene>, <scene name='pdbligand=ETE:2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL'>ETE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.19&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">blaC, ERS027646_02769 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=AE4:3,6,9,12,15-PENTAOXAHEPTADECAN-1-OL'>AE4</scene>, <scene name='pdbligand=ETE:2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL'>ETE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5nj2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nj2 OCA], [https://pdbe.org/5nj2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5nj2 RCSB], [https://www.ebi.ac.uk/pdbsum/5nj2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5nj2 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nj2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nj2 OCA], [http://pdbe.org/5nj2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nj2 RCSB], [http://www.ebi.ac.uk/pdbsum/5nj2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nj2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BLAC_MYCTU BLAC_MYCTU]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5nj2" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5nj2" style="background-color:#fffaf0;"></div>
==See Also==
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Beta-lactamase]]
[[Category: Large Structures]]
[[Category: Pannu, N S]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Tassoni, R]]
[[Category: Pannu NS]]
[[Category: Ubbink, M]]
[[Category: Tassoni R]]
[[Category: Hydrolase]]
[[Category: Ubbink M]]

Latest revision as of 13:01, 15 November 2023

Crystal structure of BlaC from Mycobacterium tuberculosis bound to phosphate

5nj2, resolution 1.19Å

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