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==CRYSTAL STRUCTURE OF AN ARCHAEBACTERIAL DNA POLYMERASE D.TOK. DEPOSITION OF SECOND NATIVE STRUCTURE AT 2.4 ANGSTROM==
==CRYSTAL STRUCTURE OF AN ARCHAEBACTERIAL DNA POLYMERASE D.TOK. DEPOSITION OF SECOND NATIVE STRUCTURE AT 2.4 ANGSTROM==
<StructureSection load='1d5a' size='340' side='right' caption='[[1d5a]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='1d5a' size='340' side='right'caption='[[1d5a]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1d5a]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Desst Desst]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D5A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1D5A FirstGlance]. <br>
<table><tr><td colspan='2'>[[1d5a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Desulfurococcus_sp._Tok Desulfurococcus sp. Tok]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D5A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1D5A FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1qqc|1qqc]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1d5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d5a OCA], [https://pdbe.org/1d5a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1d5a RCSB], [https://www.ebi.ac.uk/pdbsum/1d5a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1d5a ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1d5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d5a OCA], [http://pdbe.org/1d5a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1d5a RCSB], [http://www.ebi.ac.uk/pdbsum/1d5a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1d5a ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DPOL_DESST DPOL_DESST]] Thermostable DNA polymerase. In addition to polymerase activity, this DNA polymerase exhibits 3' to 5' exonuclease activity.<ref>PMID:8663453</ref>
[https://www.uniprot.org/uniprot/DPOL_DESST DPOL_DESST] Thermostable DNA polymerase. In addition to polymerase activity, this DNA polymerase exhibits 3' to 5' exonuclease activity.<ref>PMID:8663453</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d5/1d5a_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d5/1d5a_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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</div>
</div>
<div class="pdbe-citations 1d5a" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1d5a" style="background-color:#fffaf0;"></div>
==See Also==
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: DNA-directed DNA polymerase]]
[[Category: Desulfurococcus sp. Tok]]
[[Category: Desst]]
[[Category: Large Structures]]
[[Category: Jeruzalmi, D]]
[[Category: Jeruzalmi D]]
[[Category: Kuriyan, J]]
[[Category: Kuriyan J]]
[[Category: Lasken, R]]
[[Category: Lasken R]]
[[Category: Leighton, L]]
[[Category: Leighton L]]
[[Category: Zhao, Y]]
[[Category: Zhao Y]]
[[Category: Dna polymerase]]
[[Category: Exonuclease]]
[[Category: Rbd domain]]
[[Category: Thermostable]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/1d5a"