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==Crystal structure of the 580 germline antibody bound to circumsporozoite protein NANP 5-mer==
==Crystal structure of the 580 germline antibody bound to circumsporozoite protein NANP 5-mer==
<StructureSection load='6azm' size='340' side='right' caption='[[6azm]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='6azm' size='340' side='right'caption='[[6azm]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6azm]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AZM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AZM FirstGlance]. <br>
<table><tr><td colspan='2'>[[6azm]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AZM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6AZM FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6azm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6azm OCA], [http://pdbe.org/6azm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6azm RCSB], [http://www.ebi.ac.uk/pdbsum/6azm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6azm ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6azm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6azm OCA], [https://pdbe.org/6azm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6azm RCSB], [https://www.ebi.ac.uk/pdbsum/6azm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6azm ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CSP_PLAFA CSP_PLAFA] The circumsporozoite protein is the immunodominant surface antigen on the sporozoite (the infective stage of the malaria parasite that is transmitted from the mosquito to the vertebrate host).
==See Also==
*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
*[[3D structures of human antibody|3D structures of human antibody]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bosch, A]]
[[Category: Homo sapiens]]
[[Category: Julien, J P]]
[[Category: Large Structures]]
[[Category: Scally, S W]]
[[Category: Plasmodium falciparum]]
[[Category: Triller, G]]
[[Category: Bosch A]]
[[Category: Wardemann, H]]
[[Category: Julien JP]]
[[Category: Circumsporozoite protein]]
[[Category: Scally SW]]
[[Category: Fab]]
[[Category: Triller G]]
[[Category: Immune system]]
[[Category: Wardemann H]]
[[Category: Malaria]]
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