5odu: Difference between revisions
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==PllA lectin, monosaccharide complex== | ==PllA lectin, monosaccharide complex== | ||
<StructureSection load='5odu' size='340' side='right' caption='[[5odu]], [[Resolution|resolution]] 1.56Å' scene=''> | <StructureSection load='5odu' size='340' side='right'caption='[[5odu]], [[Resolution|resolution]] 1.56Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5odu]] is a 8 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5odu]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Photorhabdus_luminescens Photorhabdus luminescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ODU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ODU FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.56Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMG:ALPHA-METHYL-D-GALACTOSIDE'>AMG</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5odu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5odu OCA], [https://pdbe.org/5odu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5odu RCSB], [https://www.ebi.ac.uk/pdbsum/5odu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5odu ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/PLLA_PHOLL PLLA_PHOLL] Lectin that specifically binds alpha-galactoside-terminating glycoconjugates. Shows high apparent binding to the alpha-Gal epitope (Gal-alpha-1,3-Gal-beta-1,4-GlcNAc terminating glycans) as well as to Gal-alpha-1,4-GlcNAc and Gal-alpha-1,3-GalNAc. Gal-alpha-1,3-GalNAc may be one natural ligand bound by PllA both in the nematode symbiont and in infected insects.<ref>PMID:28972138</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Photorhabdus luminescens]] | ||
[[Category: | [[Category: Koehnke J]] | ||
[[Category: | [[Category: Sikandar A]] | ||