6f9k: Difference between revisions

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New page: '''Unreleased structure''' The entry 6f9k is ON HOLD Authors: Stiel, A.C., Shanmugaratnam, S., Hocker, B. Description: Tryptophan Repressor TrpR from E.coli with 5-methyl-L-tryptophan ...
 
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'''Unreleased structure'''


The entry 6f9k is ON HOLD
==Tryptophan Repressor TrpR from E.coli with 5-methyl-L-tryptophan as ligand==
 
<StructureSection load='6f9k' size='340' side='right'caption='[[6f9k]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
Authors: Stiel, A.C., Shanmugaratnam, S., Hocker, B.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6f9k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F9K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6F9K FirstGlance]. <br>
Description: Tryptophan Repressor TrpR from E.coli with 5-methyl-L-tryptophan as ligand
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.399&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=D0Q:5-methyl-L-tryptophan'>D0Q</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[Category: Hocker, B]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6f9k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f9k OCA], [https://pdbe.org/6f9k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6f9k RCSB], [https://www.ebi.ac.uk/pdbsum/6f9k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6f9k ProSAT]</span></td></tr>
[[Category: Shanmugaratnam, S]]
</table>
[[Category: Stiel, A.C]]
== Function ==
[https://www.uniprot.org/uniprot/TRPR_ECOLI TRPR_ECOLI] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
__TOC__
</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Hocker B]]
[[Category: Shanmugaratnam S]]
[[Category: Stiel AC]]

Latest revision as of 10:23, 15 November 2023

Tryptophan Repressor TrpR from E.coli with 5-methyl-L-tryptophan as ligand

6f9k, resolution 1.40Å

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