6bxi: Difference between revisions
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New page: '''Unreleased structure''' The entry 6bxi is ON HOLD Authors: Xiong, S., Sicheri, F. Description: X-ray crystal structure of NDR1 kinase domain Category: Unreleased Structures [[Ca... |
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==X-ray crystal structure of NDR1 kinase domain== | |||
<StructureSection load='6bxi' size='340' side='right'caption='[[6bxi]], [[Resolution|resolution]] 2.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6bxi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BXI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BXI FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bxi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bxi OCA], [https://pdbe.org/6bxi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bxi RCSB], [https://www.ebi.ac.uk/pdbsum/6bxi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bxi ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/STK38_HUMAN STK38_HUMAN] Negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K2.<ref>PMID:7761441</ref> <ref>PMID:12493777</ref> <ref>PMID:15197186</ref> <ref>PMID:17906693</ref> | |||
==See Also== | |||
*[[Serine/threonine protein kinase 3D structures|Serine/threonine protein kinase 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Sicheri F]] | |||
[[Category: Xiong S]] | |||
