6fal: Difference between revisions

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'''Unreleased structure'''


The entry 6fal is ON HOLD
==Tryptophan Repressor TrpR from E.coli with 3-Indolepropionic acid as ligand==
 
<StructureSection load='6fal' size='340' side='right'caption='[[6fal]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
Authors: Stiel, A.C., Shanmugaratnam, S., Hocker, B.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6fal]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FAL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6FAL FirstGlance]. <br>
Description: Tryptophan Repressor TrpR from E.coli with 3-Indolepropionic acid as ligand
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOP:INDOLYLPROPIONIC+ACID'>IOP</scene></td></tr>
[[Category: Hocker, B]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6fal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fal OCA], [https://pdbe.org/6fal PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6fal RCSB], [https://www.ebi.ac.uk/pdbsum/6fal PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6fal ProSAT]</span></td></tr>
[[Category: Shanmugaratnam, S]]
</table>
[[Category: Stiel, A.C]]
== Function ==
[https://www.uniprot.org/uniprot/TRPR_ECOLI TRPR_ECOLI] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Hocker B]]
[[Category: Shanmugaratnam S]]
[[Category: Stiel AC]]
Retrieved from "https://proteopedia.org/6fal"