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[[Image:2cz9.gif|left|200px]]


{{Structure
==Crystal Structure of galactokinase from Pyrococcus horikoshi==
|PDB= 2cz9 |SIZE=350|CAPTION= <scene name='initialview01'>2cz9</scene>, resolution 1.50&Aring;
<StructureSection load='2cz9' size='340' side='right'caption='[[2cz9]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
<table><tr><td colspan='2'>[[2cz9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CZ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CZ9 FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Galactokinase Galactokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.6 2.7.1.6] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
|GENE=
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cz9 OCA], [https://pdbe.org/2cz9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cz9 RCSB], [https://www.ebi.ac.uk/pdbsum/2cz9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cz9 ProSAT], [https://www.topsan.org/Proteins/RSGI/2cz9 TOPSAN]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cz9 OCA], [http://www.ebi.ac.uk/pdbsum/2cz9 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2cz9 RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/GAL1_PYRHO GAL1_PYRHO] Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).<ref>PMID:16511293</ref>
 
== Evolutionary Conservation ==
'''Crystal Structure of galactokinase from Pyrococcus horikoshi'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cz/2cz9_consurf.spt"</scriptWhenChecked>
2CZ9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CZ9 OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Galactokinase]]
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cz9 ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pyrococcus horikoshii]]
[[Category: Pyrococcus horikoshii]]
[[Category: Single protein]]
[[Category: Inagaki E]]
[[Category: Inagaki, E.]]
[[Category: Sakamoto K]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Shinkai A]]
[[Category: Sakamoto, K.]]
[[Category: Yokoyama S]]
[[Category: Shinkai, A.]]
[[Category: Yokoyama, S.]]
[[Category: galactokinase]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:28:15 2008''

Latest revision as of 08:21, 25 October 2023

Crystal Structure of galactokinase from Pyrococcus horikoshi

2cz9, resolution 1.50Å

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