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[[Image:2cz8.gif|left|200px]]


{{Structure
==Crystal Structure of tt0972 protein from Thermus thermophilus==
|PDB= 2cz8 |SIZE=350|CAPTION= <scene name='initialview01'>2cz8</scene>, resolution 1.50&Aring;
<StructureSection load='2cz8' size='340' side='right'caption='[[2cz8]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>
<table><tr><td colspan='2'>[[2cz8]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CZ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CZ8 FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cz8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cz8 OCA], [https://pdbe.org/2cz8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cz8 RCSB], [https://www.ebi.ac.uk/pdbsum/2cz8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cz8 ProSAT], [https://www.topsan.org/Proteins/RSGI/2cz8 TOPSAN]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cz8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cz8 OCA], [http://www.ebi.ac.uk/pdbsum/2cz8 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2cz8 RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/DODEC_THET8 DODEC_THET8] May function as storage protein that sequesters various flavins and other cofactors, thereby protecting the cell against undesirable reactions mediated by the free cofactors. Binds and sequesters FMN, FAD, lumiflavin and lumichrome, and can also bind coenzyme A.<ref>PMID:17855371</ref>
 
== Evolutionary Conservation ==
'''Crystal Structure of tt0972 protein from Thermus thermophilus'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cz/2cz8_consurf.spt"</scriptWhenChecked>
2CZ8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CZ8 OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Single protein]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Thermus thermophilus]]
  </jmolCheckbox>
[[Category: Inagaki, E.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cz8 ConSurf].
[[Category: Kumei, M.]]
<div style="clear:both"></div>
[[Category: Nakano, N.]]
== References ==
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
<references/>
[[Category: Shinkai, A.]]
__TOC__
[[Category: Yokoyama, S.]]
</StructureSection>
[[Category: dodecamer]]
[[Category: Large Structures]]
[[Category: flavin]]
[[Category: Thermus thermophilus HB8]]
[[Category: flavin-adenine dinucleotide]]
[[Category: Inagaki E]]
[[Category: national project on protein structural and functional analyse]]
[[Category: Kumei M]]
[[Category: nppsfa]]
[[Category: Nakano N]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: Shinkai A]]
[[Category: rsgi]]
[[Category: Yokoyama S]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:28:15 2008''

Latest revision as of 08:21, 25 October 2023

Crystal Structure of tt0972 protein from Thermus thermophilus

2cz8, resolution 1.50Å

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