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==Second PDZ Domain (PDZ2) of PTP-BL==
==Second PDZ Domain (PDZ2) of PTP-BL==
<StructureSection load='1gm1' size='340' side='right' caption='[[1gm1]], [[NMR_Ensembles_of_Models | 35 NMR models]]' scene=''>
<StructureSection load='1gm1' size='340' side='right'caption='[[1gm1]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1gm1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GM1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GM1 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1gm1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GM1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GM1 FirstGlance]. <br>
</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gm1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gm1 OCA], [http://pdbe.org/1gm1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gm1 RCSB], [http://www.ebi.ac.uk/pdbsum/1gm1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1gm1 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gm1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gm1 OCA], [https://pdbe.org/1gm1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gm1 RCSB], [https://www.ebi.ac.uk/pdbsum/1gm1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gm1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PTN13_MOUSE PTN13_MOUSE]] Tyrosine phosphatase which regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling.  
[https://www.uniprot.org/uniprot/PTN13_MOUSE PTN13_MOUSE] Tyrosine phosphatase which regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 1gm1" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1gm1" style="background-color:#fffaf0;"></div>
==See Also==
*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lk3 transgenic mice]]
[[Category: Large Structures]]
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Mus musculus]]
[[Category: Aelen, J]]
[[Category: Aelen J]]
[[Category: Hendriks, W]]
[[Category: Hendriks W]]
[[Category: Schepens, J]]
[[Category: Schepens J]]
[[Category: Tessari, M]]
[[Category: Tessari M]]
[[Category: Vuister, G W]]
[[Category: Vuister GW]]
[[Category: Walma, T]]
[[Category: Walma T]]
[[Category: Cytoskeleton]]
[[Category: Fas interaction]]
[[Category: Hydrolase]]
[[Category: Lim interaction]]
[[Category: Pdz]]
[[Category: Ptp-bl]]
[[Category: Structural protein]]
Retrieved from "https://proteopedia.org/1gm1"