6ary: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| (2 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Crystal structure of an insecticide-resistant acetylcholinesterase mutant from the malaria vector Anopheles gambiae in complex with a difluoromethyl ketone inhibitor== | ==Crystal structure of an insecticide-resistant acetylcholinesterase mutant from the malaria vector Anopheles gambiae in complex with a difluoromethyl ketone inhibitor== | ||
<StructureSection load='6ary' size='340' side='right' caption='[[6ary]], [[Resolution|resolution]] 2.26Å' scene=''> | <StructureSection load='6ary' size='340' side='right'caption='[[6ary]], [[Resolution|resolution]] 2.26Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6ary]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ARY OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[6ary]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Anopheles_gambiae Anopheles gambiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ARY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ARY FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BT7:( | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.257Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BT7:(1~{S})-2,2-bis(fluoranyl)-1-(1-pentan-3-ylpyrazol-4-yl)ethanol'>BT7</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ary FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ary OCA], [https://pdbe.org/6ary PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ary RCSB], [https://www.ebi.ac.uk/pdbsum/6ary PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ary ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/ACES_ANOGA ACES_ANOGA] Rapidly hydrolyzes choline released into the synapse. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 19: | Line 19: | ||
</div> | </div> | ||
<div class="pdbe-citations 6ary" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 6ary" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Acetylcholinesterase 3D structures|Acetylcholinesterase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Anopheles gambiae]] | ||
[[Category: Carlier | [[Category: Large Structures]] | ||
[[Category: Cheung | [[Category: Carlier PR]] | ||
[[Category: Kalathur | [[Category: Cheung J]] | ||
[[Category: Lixuan | [[Category: Kalathur R]] | ||
[[Category: Mahmood | [[Category: Lixuan L]] | ||
[[Category: Mahmood A]] | |||
Latest revision as of 07:49, 17 October 2024
Crystal structure of an insecticide-resistant acetylcholinesterase mutant from the malaria vector Anopheles gambiae in complex with a difluoromethyl ketone inhibitor
| ||||||||||||
