2d5b: Difference between revisions

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[[Image:2d5b.jpg|left|200px]]


{{Structure
==Crystal Structure of Thermus Thermophilus Methionyl tRNA synthetase Y225F Mutant obtained in the presence of PEG6000==
|PDB= 2d5b |SIZE=350|CAPTION= <scene name='initialview01'>2d5b</scene>, resolution 1.8&Aring;
<StructureSection load='2d5b' size='340' side='right'caption='[[2d5b]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
<table><tr><td colspan='2'>[[2d5b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D5B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D5B FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine--tRNA_ligase Methionine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.10 6.1.1.10] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d5b OCA], [https://pdbe.org/2d5b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d5b RCSB], [https://www.ebi.ac.uk/pdbsum/2d5b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d5b ProSAT], [https://www.topsan.org/Proteins/RSGI/2d5b TOPSAN]</span></td></tr>
|RELATEDENTRY=[[1a8h|1A8H]], [[1woy|1WOY]], [[2d54|2D54]]
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2d5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d5b OCA], [http://www.ebi.ac.uk/pdbsum/2d5b PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2d5b RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/SYM_THET8 SYM_THET8] Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d5/2d5b_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d5b ConSurf].
<div style="clear:both"></div>


'''Crystal Structure of Thermus Thermophilus Methionyl tRNA synthetase Y225F Mutant obtained in the presence of PEG6000'''
==See Also==
 
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2D5B is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D5B OCA].
[[Category: Large Structures]]
[[Category: Methionine--tRNA ligase]]
[[Category: Single protein]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
[[Category: Ishii, R.]]
[[Category: Ishii R]]
[[Category: Konno, M.]]
[[Category: Konno M]]
[[Category: Mori, Y.]]
[[Category: Mori Y]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Takasaka R]]
[[Category: Takasaka, R.]]
[[Category: Takeda R]]
[[Category: Takeda, R.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: class 1a aar]]
[[Category: isomerase]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rossmann fold]]
[[Category: rsgi]]
[[Category: structural genomic]]
 
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Retrieved from "https://proteopedia.org/2d5b"