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==Structure of the A2A-StaR2-bRIL562-Vipadenant complex at 2.6A obtained from in meso soaking experiments.==
==Structure of the A2A-StaR2-bRIL562-Vipadenant complex at 2.6A obtained from in meso soaking experiments.==
<StructureSection load='5olh' size='340' side='right' caption='[[5olh]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='5olh' size='340' side='right'caption='[[5olh]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5olh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OLH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OLH FirstGlance]. <br>
<table><tr><td colspan='2'>[[5olh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OLH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5OLH FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9XT:3-[(4-azanyl-3-methyl-phenyl)methyl]-7-(furan-2-yl)-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine'>9XT</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5olh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5olh OCA], [http://pdbe.org/5olh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5olh RCSB], [http://www.ebi.ac.uk/pdbsum/5olh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5olh ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9XT:3-[(4-azanyl-3-methyl-phenyl)methyl]-7-(furan-2-yl)-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine'>9XT</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5olh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5olh OCA], [https://pdbe.org/5olh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5olh RCSB], [https://www.ebi.ac.uk/pdbsum/5olh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5olh ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/AA2AR_HUMAN AA2AR_HUMAN]] Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.  
[https://www.uniprot.org/uniprot/AA2AR_HUMAN AA2AR_HUMAN] Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.[https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5olh" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5olh" style="background-color:#fffaf0;"></div>
==See Also==
*[[Adenosine A2A receptor 3D structures|Adenosine A2A receptor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Brown, G A]]
[[Category: Escherichia coli]]
[[Category: Cheng, R K.Y]]
[[Category: Homo sapiens]]
[[Category: Cooke, R]]
[[Category: Large Structures]]
[[Category: Dore, A S]]
[[Category: Brown GA]]
[[Category: Errey, J C]]
[[Category: Cheng RKY]]
[[Category: Geng, T]]
[[Category: Cooke R]]
[[Category: Marshall, F H]]
[[Category: Dore AS]]
[[Category: Rucktooa, P]]
[[Category: Errey JC]]
[[Category: Segala, E]]
[[Category: Geng T]]
[[Category: Tm integral membrane protein]]
[[Category: Marshall FH]]
[[Category: Adenosine 2a receptor]]
[[Category: Rucktooa P]]
[[Category: G-protein coupled receptor]]
[[Category: Segala E]]
[[Category: Membrane protein]]
[[Category: Thermostabilizing mutation]]
Retrieved from "https://proteopedia.org/5olh"