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==CRYSTAL STRUCTURE OF THE E. COLI MANGANESE(II) SUPEROXIDE DISMUTASE MUTANT Y174F AT 0.90 ANGSTROMS RESOLUTION.==
==CRYSTAL STRUCTURE OF THE E. COLI MANGANESE(II) SUPEROXIDE DISMUTASE MUTANT Y174F AT 0.90 ANGSTROMS RESOLUTION.==
<StructureSection load='1ixb' size='340' side='right' caption='[[1ixb]], [[Resolution|resolution]] 0.90&Aring;' scene=''>
<StructureSection load='1ixb' size='340' side='right'caption='[[1ixb]], [[Resolution|resolution]] 0.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1ixb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IXB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IXB FirstGlance]. <br>
<table><tr><td colspan='2'>[[1ixb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IXB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IXB FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MH2:MANGANESE+ION,+1+HYDROXYL+COORDINATED'>MH2</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.9&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1vew|1vew]], [[1i0h|1i0h]], [[1en4|1en4]], [[1en6|1en6]], [[1i08|1i08]], [[1mmm|1mmm]], [[1ix9|1ix9]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MH2:MANGANESE+ION,+1+HYDROXYL+COORDINATED'>MH2</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ixb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ixb OCA], [https://pdbe.org/1ixb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ixb RCSB], [https://www.ebi.ac.uk/pdbsum/1ixb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ixb ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ixb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ixb OCA], [http://pdbe.org/1ixb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ixb RCSB], [http://www.ebi.ac.uk/pdbsum/1ixb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ixb ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SODM_ECOLI SODM_ECOLI]] Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.  
[https://www.uniprot.org/uniprot/SODM_ECOLI SODM_ECOLI] Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ix/1ixb_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ix/1ixb_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ixb ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ixb ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
*[[Superoxide dismutase 3D structures|Superoxide dismutase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Superoxide dismutase]]
[[Category: Large Structures]]
[[Category: Anderson, B F]]
[[Category: Anderson BF]]
[[Category: Baker, E N]]
[[Category: Baker EN]]
[[Category: Edwards, R A]]
[[Category: Edwards RA]]
[[Category: Jameson, G B]]
[[Category: Jameson GB]]
[[Category: Whittaker, J W]]
[[Category: Whittaker JW]]
[[Category: Whittaker, M M]]
[[Category: Whittaker MM]]
[[Category: Hydrogen bond reactivity]]
[[Category: Oxidoreductase]]
[[Category: Ultrahigh resolution]]
[[Category: Y174f mutant]]

Latest revision as of 06:13, 13 August 2026

CRYSTAL STRUCTURE OF THE E. COLI MANGANESE(II) SUPEROXIDE DISMUTASE MUTANT Y174F AT 0.90 ANGSTROMS RESOLUTION.

1ixb, resolution 0.90Å

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