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==Crystal structure of the Mus musculus cholesterol-regulated START protein 4 (StarD4).==
==Crystal structure of the Mus musculus cholesterol-regulated START protein 4 (StarD4).==
<StructureSection load='1jss' size='340' side='right' caption='[[1jss]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='1jss' size='340' side='right'caption='[[1jss]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1jss]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JSS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JSS FirstGlance]. <br>
<table><tr><td colspan='2'>[[1jss]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JSS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JSS FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BC005642; Unigene Cluster: Mm. 31508 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jss FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jss OCA], [http://pdbe.org/1jss PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jss RCSB], [http://www.ebi.ac.uk/pdbsum/1jss PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1jss ProSAT], [http://www.topsan.org/Proteins/NYSGXRC/1jss TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jss FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jss OCA], [https://pdbe.org/1jss PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jss RCSB], [https://www.ebi.ac.uk/pdbsum/1jss PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jss ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1jss TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/STAR4_MOUSE STAR4_MOUSE]] May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.  
[https://www.uniprot.org/uniprot/STAR4_MOUSE STAR4_MOUSE] May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/js/1jss_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/js/1jss_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lk3 transgenic mice]]
[[Category: Large Structures]]
[[Category: Breslow, J L]]
[[Category: Mus musculus]]
[[Category: Burley, S K]]
[[Category: Breslow JL]]
[[Category: Structural genomic]]
[[Category: Burley SK]]
[[Category: Romanowski, M J]]
[[Category: Romanowski MJ]]
[[Category: Soccio, R E]]
[[Category: Soccio RE]]
[[Category: Lipid binding protein]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
[[Category: PSI, Protein structure initiative]]
[[Category: Start domain]]

Latest revision as of 03:44, 6 June 2025

Crystal structure of the Mus musculus cholesterol-regulated START protein 4 (StarD4).

1jss, resolution 2.20Å

Drag the structure with the mouse to rotate

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