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[[Image:2dlu.jpg|left|200px]]


{{Structure
==Solution structure of the second PDZ domain of human InaD-like protein==
|PDB= 2dlu |SIZE=350|CAPTION= <scene name='initialview01'>2dlu</scene>
<StructureSection load='2dlu' size='340' side='right'caption='[[2dlu]]' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[2dlu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DLU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DLU FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
|GENE= INADL, PATJ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dlu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dlu OCA], [https://pdbe.org/2dlu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dlu RCSB], [https://www.ebi.ac.uk/pdbsum/2dlu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dlu ProSAT], [https://www.topsan.org/Proteins/RSGI/2dlu TOPSAN]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dlu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dlu OCA], [http://www.ebi.ac.uk/pdbsum/2dlu PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2dlu RCSB]</span>
[https://www.uniprot.org/uniprot/INADL_HUMAN INADL_HUMAN] Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons.<ref>PMID:11927608</ref>
}}
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
'''Solution structure of the second PDZ domain of human InaD-like protein'''
Check<jmol>
 
  <jmolCheckbox>
 
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dl/2dlu_consurf.spt"</scriptWhenChecked>
==About this Structure==
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
2DLU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DLU OCA].  
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dlu ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Hayashi, F.]]
[[Category: Hayashi F]]
[[Category: Inoue, K.]]
[[Category: Inoue K]]
[[Category: Izumi, K.]]
[[Category: Izumi K]]
[[Category: Kurosaki, C.]]
[[Category: Kurosaki C]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: Yoshida M]]
[[Category: Yoshida, M.]]
[[Category: hinadl]]
[[Category: inad-like protein]]
[[Category: inadl]]
[[Category: inadl protein]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: pals1-associated tight junction protein]]
[[Category: patj]]
[[Category: pdz domain]]
[[Category: protein associated to tight junction]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:36:22 2008''

Latest revision as of 18:43, 29 May 2024

Solution structure of the second PDZ domain of human InaD-like protein

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