2do5: Difference between revisions

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[[Image:2do5.gif|left|200px]]


{{Structure
==Solution structure of the SAP domain of human splicing factor 3B subunit 2==
|PDB= 2do5 |SIZE=350|CAPTION= <scene name='initialview01'>2do5</scene>
<StructureSection load='2do5' size='340' side='right'caption='[[2do5]]' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[2do5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DO5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DO5 FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
|GENE= SF3B2, SAP145 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2do5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2do5 OCA], [https://pdbe.org/2do5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2do5 RCSB], [https://www.ebi.ac.uk/pdbsum/2do5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2do5 ProSAT], [https://www.topsan.org/Proteins/RSGI/2do5 TOPSAN]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2do5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2do5 OCA], [http://www.ebi.ac.uk/pdbsum/2do5 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2do5 RCSB]</span>
[https://www.uniprot.org/uniprot/SF3B2_HUMAN SF3B2_HUMAN] Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
}}


'''Solution structure of the SAP domain of human splicing factor 3B subunit 2'''
==See Also==
 
*[[Pre-mRNA splicing factors 3D structures|Pre-mRNA splicing factors 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2DO5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DO5 OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Inoue, M.]]
[[Category: Inoue M]]
[[Category: Kigawa, T.]]
[[Category: Kigawa T]]
[[Category: Muto, Y.]]
[[Category: Muto Y]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Shirouzu M]]
[[Category: Shirouzu, M.]]
[[Category: Suzuki S]]
[[Category: Suzuki, S.]]
[[Category: Terada T]]
[[Category: Terada, T.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: sap domain]]
[[Category: structural genomic]]
 
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Retrieved from "https://proteopedia.org/2do5"