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==Crystal structure of the N-terminal domain of the secretin GspD from ETEC determined with the assistance of a nanobody==
==Crystal structure of the N-terminal domain of the secretin GspD from ETEC determined with the assistance of a nanobody==
<StructureSection load='3ezj' size='340' side='right' caption='[[3ezj]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='3ezj' size='340' side='right'caption='[[3ezj]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3ezj]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Camelus_glama Camelus glama] and [http://en.wikipedia.org/wiki/Ecoh1 Ecoh1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EZJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EZJ FirstGlance]. <br>
<table><tr><td colspan='2'>[[3ezj]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_ETEC_H10407 Escherichia coli ETEC H10407] and [https://en.wikipedia.org/wiki/Lama_glama Lama glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EZJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EZJ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gspD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=316401 ECOH1]), NBGSPD_7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9844 Camelus glama])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ezj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ezj OCA], [http://pdbe.org/3ezj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ezj RCSB], [http://www.ebi.ac.uk/pdbsum/3ezj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ezj ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ezj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ezj OCA], [https://pdbe.org/3ezj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ezj RCSB], [https://www.ebi.ac.uk/pdbsum/3ezj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ezj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q707C1_ECOLX Q707C1_ECOLX]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 3ezj" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3ezj" style="background-color:#fffaf0;"></div>
==See Also==
*[[General secretion pathway protein 3D structures|General secretion pathway protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Camelus glama]]
[[Category: Escherichia coli ETEC H10407]]
[[Category: Ecoh1]]
[[Category: Lama glama]]
[[Category: Hol, W G]]
[[Category: Large Structures]]
[[Category: Korotkov, K V]]
[[Category: Hol WG]]
[[Category: Pardon, E]]
[[Category: Korotkov KV]]
[[Category: Steyaert, J]]
[[Category: Pardon E]]
[[Category: Complex]]
[[Category: Steyaert J]]
[[Category: General secretory pathway]]
[[Category: Immune system]]
[[Category: Protein transport]]
[[Category: Secretin]]
[[Category: Single chain antibody]]