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[[Image:2drv.gif|left|200px]]


{{Structure
==Structure of PH1069 protein from Pyrococcus horikoshii OT3==
|PDB= 2drv |SIZE=350|CAPTION= <scene name='initialview01'>2drv</scene>, resolution 1.60&Aring;
<StructureSection load='2drv' size='340' side='right'caption='[[2drv]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
<table><tr><td colspan='2'>[[2drv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DRV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DRV FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2drv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2drv OCA], [https://pdbe.org/2drv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2drv RCSB], [https://www.ebi.ac.uk/pdbsum/2drv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2drv ProSAT], [https://www.topsan.org/Proteins/RSGI/2drv TOPSAN]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2drv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2drv OCA], [http://www.ebi.ac.uk/pdbsum/2drv PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2drv RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/TYW31_PYRHO TYW31_PYRHO] S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.[HAMAP-Rule:MF_00266]
 
== Evolutionary Conservation ==
'''Structure of PH1069 protein from Pyrococcus horikoshii OT3'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dr/2drv_consurf.spt"</scriptWhenChecked>
2DRV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DRV OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: Pyrococcus horikoshii]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Single protein]]
  </jmolCheckbox>
[[Category: Kunishima, N.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2drv ConSurf].
[[Category: Lokanath, N K.]]
<div style="clear:both"></div>
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
__TOC__
[[Category: hypothetical protein]]
</StructureSection>
[[Category: national project on protein structural and functional analyse]]
[[Category: Large Structures]]
[[Category: nppsfa]]
[[Category: Pyrococcus horikoshii OT3]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: Kunishima N]]
[[Category: rsgi]]
[[Category: Lokanath NK]]
[[Category: structural genomic]]
[[Category: unknown function]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:38:34 2008''

Latest revision as of 05:10, 17 October 2024

Structure of PH1069 protein from Pyrococcus horikoshii OT3

2drv, resolution 1.60Å

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