5a15: Difference between revisions
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==Crystal structure of the BTB domain of human KCTD16== | ==Crystal structure of the BTB domain of human KCTD16== | ||
<StructureSection load='5a15' size='340' side='right' caption='[[5a15]], [[Resolution|resolution]] 2.76Å' scene=''> | <StructureSection load='5a15' size='340' side='right'caption='[[5a15]], [[Resolution|resolution]] 2.76Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5a15]] is a 15 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5a15]] is a 15 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A15 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5A15 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.76Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5a15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a15 OCA], [https://pdbe.org/5a15 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5a15 RCSB], [https://www.ebi.ac.uk/pdbsum/5a15 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5a15 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/KCD16_HUMAN KCD16_HUMAN] Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 22: | Line 22: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Arrowsmith | [[Category: Large Structures]] | ||
[[Category: Bountra | [[Category: Arrowsmith CH]] | ||
[[Category: Bullock | [[Category: Bountra C]] | ||
[[Category: Burgess-Brown | [[Category: Bullock A]] | ||
[[Category: Canning | [[Category: Burgess-Brown NA]] | ||
[[Category: Chalk | [[Category: Canning P]] | ||
[[Category: Clarke | [[Category: Chalk R]] | ||
[[Category: Dixon Clarke SE]] | |||
[[Category: Doutch | [[Category: Doutch J]] | ||
[[Category: Edwards | [[Category: Edwards AM]] | ||
[[Category: Fitzpatrick | [[Category: Fitzpatrick F]] | ||
[[Category: Goubin | [[Category: Goubin S]] | ||
[[Category: Kopec | [[Category: Kopec J]] | ||
[[Category: Krojer | [[Category: Krojer T]] | ||
[[Category: Pinkas | [[Category: Pinkas DM]] | ||
[[Category: Sanvitale | [[Category: Sanvitale CE]] | ||
[[Category: Solcan | [[Category: Solcan N]] | ||
[[Category: Tallant | [[Category: Tallant C]] | ||
[[Category: Talon | [[Category: Talon R]] | ||
[[Category: Wiggers | [[Category: Wiggers HJ]] | ||
[[Category: | [[Category: Von Delft F]] | ||