6c6p: Difference between revisions
From Proteopedia
Jump to navigationJump to search
New page: '''Unreleased structure''' The entry 6c6p is ON HOLD Authors: Padyana, A.K., Jin, L. Description: Human squalene epoxidase structure with NB-598 Category: Unreleased Structures [[C... |
No edit summary |
||
| (7 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Human squalene epoxidase (SQLE, squalene monooxygenase) structure with FAD and NB-598== | |||
<StructureSection load='6c6p' size='340' side='right'caption='[[6c6p]], [[Resolution|resolution]] 2.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6c6p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C6P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6C6P FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CPS:3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE'>CPS</scene>, <scene name='pdbligand=EMV:(2E)-N-({3-[([3,3-bithiophen]-5-yl)methoxy]phenyl}methyl)-N-ethyl-6,6-dimethylhept-2-en-4-yn-1-amine'>EMV</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6c6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c6p OCA], [https://pdbe.org/6c6p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6c6p RCSB], [https://www.ebi.ac.uk/pdbsum/6c6p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6c6p ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ERG1_HUMAN ERG1_HUMAN] Catalyzes the first oxygenation step in sterol biosynthesis and is suggested to be one of the rate-limiting enzymes in this pathway. | |||
==See Also== | |||
*[[Epoxidase 3D structures|Epoxidase 3D structures]] | |||
*[[Monooxygenase 3D structures|Monooxygenase 3D structures]] | |||
[[Category: | __TOC__ | ||
[[Category: Jin | </StructureSection> | ||
[[Category: Padyana | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | |||
[[Category: Jin L]] | |||
[[Category: Padyana AK]] | |||
Latest revision as of 14:26, 13 March 2024
Human squalene epoxidase (SQLE, squalene monooxygenase) structure with FAD and NB-598
| ||||||||||||
