6c79: Difference between revisions
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New page: '''Unreleased structure''' The entry 6c79 is ON HOLD Authors: Coates, L., Langan, P.S., Vandavasi, V.G., Cooper, S.J., Weiss, K.L., Ginell, S.L., Parks, J.M. Description: Conformationa... |
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==Conformational Changes in a Class A Beta lactamase that Prime it for Catalysis== | |||
<StructureSection load='6c79' size='340' side='right'caption='[[6c79]], [[Resolution|resolution]] 1.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6c79]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C79 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6C79 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.1Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CE3:(6R,7R)-3-(ACETYLOXYMETHYL)-7-[[(2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-METHOXYIMINO-ETHANOYL]AMINO]-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC+ACID'>CE3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6c79 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c79 OCA], [https://pdbe.org/6c79 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6c79 RCSB], [https://www.ebi.ac.uk/pdbsum/6c79 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6c79 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/BLT1_ECOLX BLT1_ECOLX] Has strong cefotaxime-hydrolyzing activity. | |||
==See Also== | |||
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: Coates | [[Category: Escherichia coli]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Coates L]] | ||
[[Category: | [[Category: Cooper SJ]] | ||
[[Category: Parks | [[Category: Ginell SL]] | ||
[[Category: | [[Category: Langan PS]] | ||
[[Category: | [[Category: Parks JM]] | ||
[[Category: Vandavasi VG]] | |||
[[Category: Weiss KL]] | |||
Latest revision as of 14:26, 13 March 2024
Conformational Changes in a Class A Beta lactamase that Prime it for Catalysis
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