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==Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with a Lys-containing peptide==
==Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with a Lys-containing peptide==
<StructureSection load='6b0u' size='340' side='right' caption='[[6b0u]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='6b0u' size='340' side='right'caption='[[6b0u]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6b0u]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B0U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B0U FirstGlance]. <br>
<table><tr><td colspan='2'>[[6b0u]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B0U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6B0U FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6b0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b0u OCA], [http://pdbe.org/6b0u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b0u RCSB], [http://www.ebi.ac.uk/pdbsum/6b0u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b0u ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6b0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b0u OCA], [https://pdbe.org/6b0u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6b0u RCSB], [https://www.ebi.ac.uk/pdbsum/6b0u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6b0u ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/EIS_MYCTU EIS_MYCTU]] May participate in pathogenesis, possibly by enhancing survival of the bacteria in host macrophages during infection.<ref>PMID:10629183</ref>
[https://www.uniprot.org/uniprot/EIS_MYCTU EIS_MYCTU] May participate in pathogenesis, possibly by enhancing survival of the bacteria in host macrophages during infection.<ref>PMID:10629183</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Biswas, T]]
[[Category: Large Structures]]
[[Category: Garneau-Tsodikova, S]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Pang, A H]]
[[Category: Biswas T]]
[[Category: Tsodikov, O V]]
[[Category: Garneau-Tsodikova S]]
[[Category: Acetylation]]
[[Category: Pang AH]]
[[Category: Aminoglycoside]]
[[Category: Tsodikov OV]]
[[Category: Drug resistance]]
[[Category: Histone acetylation]]
[[Category: Transferase]]
[[Category: Tuberculosis]]
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