1m21: Difference between revisions

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==Crystal structure analysis of the peptide amidase PAM in complex with the competitive inhibitor chymostatin==
==Crystal structure analysis of the peptide amidase PAM in complex with the competitive inhibitor chymostatin==
<StructureSection load='1m21' size='340' side='right' caption='[[1m21]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='1m21' size='340' side='right'caption='[[1m21]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1m21]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"pseudomonas_maltophilia"_hugh_and_ryschenkow_1961 "pseudomonas maltophilia" hugh and ryschenkow 1961]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M21 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1M21 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1m21]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Stenotrophomonas_maltophilia Stenotrophomonas maltophilia] and [https://en.wikipedia.org/wiki/Streptomyces_hygroscopicus Streptomyces hygroscopicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M21 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M21 FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSI:AMINO-(2-IMINO-HEXAHYDRO-PYRIMIDIN-4-YL)-ACETIC+ACID'>CSI</scene>, <scene name='pdbligand=PHA:PHENYLALANINAL'>PHA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1m22|1m22]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSI:AMINO-(2-IMINO-HEXAHYDRO-PYRIMIDIN-4-YL)-ACETIC+ACID'>CSI</scene>, <scene name='pdbligand=PHA:PHENYLALANINAL'>PHA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1m21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m21 OCA], [http://pdbe.org/1m21 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1m21 RCSB], [http://www.ebi.ac.uk/pdbsum/1m21 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1m21 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m21 OCA], [https://pdbe.org/1m21 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m21 RCSB], [https://www.ebi.ac.uk/pdbsum/1m21 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m21 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8RJN5_STEMA Q8RJN5_STEMA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m2/1m21_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m2/1m21_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Pseudomonas maltophilia hugh and ryschenkow 1961]]
[[Category: Large Structures]]
[[Category: Buldt, G]]
[[Category: Stenotrophomonas maltophilia]]
[[Category: Granzin, J]]
[[Category: Streptomyces hygroscopicus]]
[[Category: Kula, M R]]
[[Category: Buldt G]]
[[Category: Labahn, J]]
[[Category: Granzin J]]
[[Category: Neumann, S]]
[[Category: Kula M-R]]
[[Category: Core: eleven-stranded beta-sheet]]
[[Category: Labahn J]]
[[Category: Covered: double layers of alpha helices on top and bottom]]
[[Category: Neumann S]]
[[Category: Hydrolase]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Protein-inhibitor complex]]
Retrieved from "https://proteopedia.org/1m21"