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[[Image:2e7c.jpg|left|200px]]


{{Structure
==Solution structure of the 6th Ig-like domain from human Myosin-binding protein C, fast-type==
|PDB= 2e7c |SIZE=350|CAPTION= <scene name='initialview01'>2e7c</scene>
<StructureSection load='2e7c' size='340' side='right'caption='[[2e7c]]' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[2e7c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E7C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E7C FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
|GENE= MYBPC2, MYBPCF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e7c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e7c OCA], [https://pdbe.org/2e7c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e7c RCSB], [https://www.ebi.ac.uk/pdbsum/2e7c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e7c ProSAT], [https://www.topsan.org/Proteins/RSGI/2e7c TOPSAN]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e7c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e7c OCA], [http://www.ebi.ac.uk/pdbsum/2e7c PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2e7c RCSB]</span>
[https://www.uniprot.org/uniprot/MYPC2_HUMAN MYPC2_HUMAN] Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
}}
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
'''Solution structure of the 6th Ig-like domain from human Myosin-binding protein C, fast-type'''
Check<jmol>
 
  <jmolCheckbox>
 
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e7/2e7c_consurf.spt"</scriptWhenChecked>
==About this Structure==
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
2E7C is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E7C OCA].  
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2e7c ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Hayashi, F.]]
[[Category: Hayashi F]]
[[Category: Nagashima, T.]]
[[Category: Nagashima T]]
[[Category: Qin, X R.]]
[[Category: Qin XR]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: c-protein]]
[[Category: fast mybp-c]]
[[Category: fast-type]]
[[Category: ig-like domain]]
[[Category: myosin-binding protein c]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: skeletal muscle fast-isoform]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:44:50 2008''

Latest revision as of 18:48, 29 May 2024

Solution structure of the 6th Ig-like domain from human Myosin-binding protein C, fast-type

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