1n87: Difference between revisions

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==Solution structure of the U-box of Prp19==
==Solution structure of the U-box of Prp19==
<StructureSection load='1n87' size='340' side='right' caption='[[1n87]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='1n87' size='340' side='right'caption='[[1n87]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1n87]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N87 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1N87 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1n87]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N87 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N87 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Prp19 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1n87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n87 OCA], [http://pdbe.org/1n87 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1n87 RCSB], [http://www.ebi.ac.uk/pdbsum/1n87 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1n87 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n87 OCA], [https://pdbe.org/1n87 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n87 RCSB], [https://www.ebi.ac.uk/pdbsum/1n87 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n87 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PRP19_YEAST PRP19_YEAST]] Involved in pre-mRNA splicing. Acts a central component of the NTC complex (or PRP19-associated complex) that associates to the spliceosome to mediate conformational rearrangement or to stabilize the structure of the spliceosome after U4 snRNA dissociation, which leads to spliceosome maturation. Involved in DNA repair.  
[https://www.uniprot.org/uniprot/PRP19_YEAST PRP19_YEAST] Involved in pre-mRNA splicing. Acts a central component of the NTC complex (or PRP19-associated complex) that associates to the spliceosome to mediate conformational rearrangement or to stabilize the structure of the spliceosome after U4 snRNA dissociation, which leads to spliceosome maturation. Involved in DNA repair.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 1n87" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1n87" style="background-color:#fffaf0;"></div>
==See Also==
*[[Pre-mRNA splicing factors 3D structures|Pre-mRNA splicing factors 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 18824]]
[[Category: Large Structures]]
[[Category: Chazin, W J]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Kooi, C W.Vander]]
[[Category: Chazin WJ]]
[[Category: Ohi, M D]]
[[Category: Ohi MD]]
[[Category: E3 ligase]]
[[Category: Vander Kooi CW]]
[[Category: Ligase-cell cycle complex]]
[[Category: U-box]]
[[Category: Ubiquitin ligase]]
Retrieved from "https://proteopedia.org/1n87"