1ocs: Difference between revisions
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==Crystal structure of the yeast PX-doamin protein Grd19p (sorting nexin3) complexed to phosphatidylinosytol-3-phosphate.== | ==Crystal structure of the yeast PX-doamin protein Grd19p (sorting nexin3) complexed to phosphatidylinosytol-3-phosphate.== | ||
<StructureSection load='1ocs' size='340' side='right' caption='[[1ocs]], [[Resolution|resolution]] 2.03Å' scene=''> | <StructureSection load='1ocs' size='340' side='right'caption='[[1ocs]], [[Resolution|resolution]] 2.03Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1ocs]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1ocs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OCS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OCS FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.03Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ocs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ocs OCA], [https://pdbe.org/1ocs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ocs RCSB], [https://www.ebi.ac.uk/pdbsum/1ocs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ocs ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/SNX3_YEAST SNX3_YEAST] Required for retention of late Golgi membrane proteins. Component of the retrieval machinery that functions by direct interaction with the cytosolic tails of certain TGN membrane proteins during the sorting/budding process at the prevacuolar compartment. Binds phosphatidylinositol 3-phosphate (PtdIns(P3)).<ref>PMID:9456318</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oc/1ocs_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oc/1ocs_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| Line 30: | Line 29: | ||
</div> | </div> | ||
<div class="pdbe-citations 1ocs" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 1ocs" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Sorting nexin 3D structures|Sorting nexin 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Aufrere | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Blondeau | [[Category: Aufrere R]] | ||
[[Category: Cheruel | [[Category: Blondeau K]] | ||
[[Category: Collinet | [[Category: Cheruel S]] | ||
[[Category: Graille | [[Category: Collinet B]] | ||
[[Category: Henkes | [[Category: De La Torre F]] | ||
[[Category: Janin | [[Category: Graille M]] | ||
[[Category: Leulliot | [[Category: Henkes G]] | ||
[[Category: | [[Category: Janin J]] | ||
[[Category: | [[Category: Leulliot N]] | ||
[[Category: | [[Category: Li De La Sierra-Gallay I]] | ||
[[Category: | [[Category: Minard P]] | ||
[[Category: Sorel | [[Category: Poupon A]] | ||
[[Category: Tilbeurgh | [[Category: Savarin P]] | ||
[[Category: Sorel I]] | |||
[[Category: Zhou | [[Category: Van Tilbeurgh H]] | ||
[[Category: Zhou CZ]] | |||
