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==Crystal structure of 2-methylcitrate dehydratase (PrpD) from Salmonella enterica==
==Crystal structure of 2-methylcitrate dehydratase (PrpD) from Salmonella enterica==
<StructureSection load='5mvi' size='340' side='right' caption='[[5mvi]], [[Resolution|resolution]] 3.05&Aring;' scene=''>
<StructureSection load='5mvi' size='340' side='right'caption='[[5mvi]], [[Resolution|resolution]] 3.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5mvi]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MVI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MVI FirstGlance]. <br>
<table><tr><td colspan='2'>[[5mvi]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica Salmonella enterica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MVI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MVI FirstGlance]. <br>
</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-methylcitrate_dehydratase 2-methylcitrate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.79 4.2.1.79] </span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.05&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mvi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mvi OCA], [http://pdbe.org/5mvi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mvi RCSB], [http://www.ebi.ac.uk/pdbsum/5mvi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mvi ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mvi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mvi OCA], [https://pdbe.org/5mvi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mvi RCSB], [https://www.ebi.ac.uk/pdbsum/5mvi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mvi ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PRPD_SALTI PRPD_SALTI] Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the dehydration of 2-methylcitrate (2-MC) to yield the cis isomer of 2-methyl-aconitate. Could also catalyze the dehydration of citrate and the hydration of cis-aconitate.[UniProtKB:P74840]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: 2-methylcitrate dehydratase]]
[[Category: Large Structures]]
[[Category: Baker, G E]]
[[Category: Salmonella enterica]]
[[Category: Race, P R]]
[[Category: Baker GE]]
[[Category: Dehydratase]]
[[Category: Race PR]]
[[Category: Lyase]]

Latest revision as of 17:51, 8 November 2023

Crystal structure of 2-methylcitrate dehydratase (PrpD) from Salmonella enterica

5mvi, resolution 3.05Å

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