5k2b: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
 
(One intermediate revision by the same user not shown)
Line 1: Line 1:


==2.5 angstrom A2a adenosine receptor structure with MR phasing using XFEL data==
==2.5 angstrom A2a adenosine receptor structure with MR phasing using XFEL data==
<StructureSection load='5k2b' size='340' side='right' caption='[[5k2b]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='5k2b' size='340' side='right'caption='[[5k2b]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5k2b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K2B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5K2B FirstGlance]. <br>
<table><tr><td colspan='2'>[[5k2b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K2B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5K2B FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLB:(2S)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLB</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=ZMA:4-{2-[(7-AMINO-2-FURAN-2-YL[1,2,4]TRIAZOLO[1,5-A][1,3,5]TRIAZIN-5-YL)AMINO]ETHYL}PHENOL'>ZMA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5k2a|5k2a]], [[5k2c|5k2c]], [[5k2d|5k2d]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLB:(2S)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLB</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=ZMA:4-{2-[(7-AMINO-2-FURAN-2-YL[1,2,4]TRIAZOLO[1,5-A][1,3,5]TRIAZIN-5-YL)AMINO]ETHYL}PHENOL'>ZMA</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ADORA2A, ADORA2, cybC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5k2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k2b OCA], [https://pdbe.org/5k2b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5k2b RCSB], [https://www.ebi.ac.uk/pdbsum/5k2b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5k2b ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5k2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k2b OCA], [http://pdbe.org/5k2b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5k2b RCSB], [http://www.ebi.ac.uk/pdbsum/5k2b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5k2b ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/AA2AR_HUMAN AA2AR_HUMAN]] Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.  
[https://www.uniprot.org/uniprot/AA2AR_HUMAN AA2AR_HUMAN] Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.[https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 20: Line 19:
</div>
</div>
<div class="pdbe-citations 5k2b" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5k2b" style="background-color:#fffaf0;"></div>
==See Also==
*[[Adenosine A2A receptor 3D structures|Adenosine A2A receptor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Aquila, A]]
[[Category: Homo sapiens]]
[[Category: Barty, A]]
[[Category: Large Structures]]
[[Category: Batyuk, A]]
[[Category: Aquila A]]
[[Category: Boutet, S]]
[[Category: Barty A]]
[[Category: Cherezov, V]]
[[Category: Batyuk A]]
[[Category: Fromme, P]]
[[Category: Boutet S]]
[[Category: GPCR, GPCR Network]]
[[Category: Cherezov V]]
[[Category: Galli, L]]
[[Category: Fromme P]]
[[Category: Gati, C]]
[[Category: Galli L]]
[[Category: Han, G W]]
[[Category: Gati C]]
[[Category: Hunter, M S]]
[[Category: Han GW]]
[[Category: Ishchenko, A]]
[[Category: Hunter MS]]
[[Category: James, D]]
[[Category: Ishchenko A]]
[[Category: Katritch, V]]
[[Category: James D]]
[[Category: Lee, M Y]]
[[Category: Katritch V]]
[[Category: Li, C]]
[[Category: Lee M-Y]]
[[Category: Liang, M]]
[[Category: Li C]]
[[Category: Liu, W]]
[[Category: Liang M]]
[[Category: Liu, Z J]]
[[Category: Liu W]]
[[Category: Nelson, G]]
[[Category: Liu Z-J]]
[[Category: Popov, P]]
[[Category: Nelson G]]
[[Category: Pu, M]]
[[Category: Popov P]]
[[Category: Spence, J C.H]]
[[Category: Pu M]]
[[Category: Stauch, B]]
[[Category: Spence JCH]]
[[Category: Stevens, R C]]
[[Category: Stauch B]]
[[Category: Weierstall, U]]
[[Category: Stevens RC]]
[[Category: White, T A]]
[[Category: Weierstall U]]
[[Category: Zhao, Y]]
[[Category: White TA]]
[[Category: A2a adenosine receptor]]
[[Category: Zhao Y]]
[[Category: Gpcr]]
[[Category: Gpcr network]]
[[Category: Membrane protein]]
[[Category: Psi-biology]]
[[Category: Structural genomic]]
Retrieved from "https://proteopedia.org/5k2b"