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==RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 BETA CHAIN==
==RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 BETA CHAIN==
<StructureSection load='1pfr' size='340' side='right' caption='[[1pfr]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='1pfr' size='340' side='right'caption='[[1pfr]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1pfr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PFR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PFR FirstGlance]. <br>
<table><tr><td colspan='2'>[[1pfr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PFR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PFR FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonucleoside-diphosphate_reductase Ribonucleoside-diphosphate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.4.1 1.17.4.1] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pfr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pfr OCA], [http://pdbe.org/1pfr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1pfr RCSB], [http://www.ebi.ac.uk/pdbsum/1pfr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1pfr ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pfr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pfr OCA], [https://pdbe.org/1pfr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pfr RCSB], [https://www.ebi.ac.uk/pdbsum/1pfr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pfr ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RIR2_ECOLI RIR2_ECOLI]] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R2 contains the tyrosyl radical required for catalysis.  
[https://www.uniprot.org/uniprot/RIR2_ECOLI RIR2_ECOLI] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R2 contains the tyrosyl radical required for catalysis.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 1pfr" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1pfr" style="background-color:#fffaf0;"></div>
==See Also==
*[[Ribonucleotide reductase 3D structures|Ribonucleotide reductase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Ribonucleoside-diphosphate reductase]]
[[Category: Large Structures]]
[[Category: Aberg, A]]
[[Category: Aberg A]]
[[Category: Eklund, H]]
[[Category: Eklund H]]
[[Category: Hajdu, J]]
[[Category: Hajdu J]]
[[Category: Logan, D T]]
[[Category: Logan DT]]
[[Category: Nordlund, P]]
[[Category: Nordlund P]]
[[Category: Regnstrom, K]]
[[Category: Regnstrom K]]
[[Category: Su, X D]]
[[Category: Su XD]]
[[Category: Acting on ribose 2'-oh]]
[[Category: Dna replication]]
[[Category: Iron]]
[[Category: Oxidoreductase]]
[[Category: Reductase]]
Retrieved from "https://proteopedia.org/1pfr"