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==Crystal structure of FIP-Fve fungal immunomodulatory protein==
==Crystal structure of FIP-Fve fungal immunomodulatory protein==
<StructureSection load='1osy' size='340' side='right' caption='[[1osy]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='1osy' size='340' side='right'caption='[[1osy]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1osy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Flammulina_velutipes Flammulina velutipes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OSY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OSY FirstGlance]. <br>
<table><tr><td colspan='2'>[[1osy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Flammulina_velutipes Flammulina velutipes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OSY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OSY FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=BR:BROMIDE+ION'>BR</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1osy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1osy OCA], [http://pdbe.org/1osy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1osy RCSB], [http://www.ebi.ac.uk/pdbsum/1osy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1osy ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1osy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1osy OCA], [https://pdbe.org/1osy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1osy RCSB], [https://www.ebi.ac.uk/pdbsum/1osy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1osy ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FVE_FLAVE FVE_FLAVE]] Lectin with specificity for complex cell-surface carbohydrates. Possesses immunomodulatory activity, stimulates lymphocyte mitogenesis, suppresses systemic anaphylaxis reactions and edema, enhances transcription of IL-2, IFN-gamma and TNF-alpha and hemagglutinates red blood cells.  
[https://www.uniprot.org/uniprot/FVE_FLAVE FVE_FLAVE] Lectin with specificity for complex cell-surface carbohydrates. Possesses immunomodulatory activity, stimulates lymphocyte mitogenesis, suppresses systemic anaphylaxis reactions and edema, enhances transcription of IL-2, IFN-gamma and TNF-alpha and hemagglutinates red blood cells.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Flammulina velutipes]]
[[Category: Flammulina velutipes]]
[[Category: Chua, K Y]]
[[Category: Large Structures]]
[[Category: Joseph, J S]]
[[Category: Chua KY]]
[[Category: Kolatkar, P R]]
[[Category: Joseph JS]]
[[Category: Palasingam, P]]
[[Category: Kolatkar PR]]
[[Category: Robinson, H]]
[[Category: Palasingam P]]
[[Category: Seow, S V]]
[[Category: Robinson H]]
[[Category: Shai, V]]
[[Category: Seow SV]]
[[Category: Fibronectin fold]]
[[Category: Shai V]]
[[Category: Fungal protein]]
[[Category: Hemagglutination]]
[[Category: Immune system]]
[[Category: Immunomodulatory]]
[[Category: Lectin]]
[[Category: Sugar binding protein]]
Retrieved from "https://proteopedia.org/1osy"