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[[Image:2eo8.jpg|left|200px]]


{{Structure
==Crystal structure of a mutant pyrrolidone carboxyl peptidase (A199P) from P. furiosus==
|PDB= 2eo8 |SIZE=350|CAPTION= <scene name='initialview01'>2eo8</scene>, resolution 2.30&Aring;
<StructureSection load='2eo8' size='340' side='right'caption='[[2eo8]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[2eo8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EO8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EO8 FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyroglutamyl-peptidase_I Pyroglutamyl-peptidase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.19.3 3.4.19.3] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
|GENE=  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eo8 OCA], [https://pdbe.org/2eo8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eo8 RCSB], [https://www.ebi.ac.uk/pdbsum/2eo8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eo8 ProSAT], [https://www.topsan.org/Proteins/RSGI/2eo8 TOPSAN]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2eo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eo8 OCA], [http://www.ebi.ac.uk/pdbsum/2eo8 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2eo8 RCSB]</span>
[https://www.uniprot.org/uniprot/PCP_PYRFU PCP_PYRFU] Removes 5-oxoproline from various penultimate amino acid residues except L-proline.[HAMAP-Rule:MF_00417]
}}
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
'''Crystal structure of a mutant pyrrolidone carboxyl peptidase (A199P) from P. furiosus'''
Check<jmol>
 
  <jmolCheckbox>
 
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eo/2eo8_consurf.spt"</scriptWhenChecked>
==About this Structure==
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
2EO8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EO8 OCA].  
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2eo8 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pyrococcus furiosus]]
[[Category: Pyrococcus furiosus]]
[[Category: Pyroglutamyl-peptidase I]]
[[Category: Okazaki N]]
[[Category: Single protein]]
[[Category: Sakamoto K]]
[[Category: Okazaki, N.]]
[[Category: Yutani K]]
[[Category: Sakamoto, K.]]
[[Category: Yutani, K.]]
[[Category: hydrolase]]
[[Category: pcp]]
[[Category: pgp-i]]
[[Category: protease]]
[[Category: pyrococcus furiosus]]
[[Category: pyroglutamyl-peptidase i]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:51:42 2008''

Latest revision as of 08:43, 25 October 2023

Crystal structure of a mutant pyrrolidone carboxyl peptidase (A199P) from P. furiosus

2eo8, resolution 2.30Å

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