2eqy: Difference between revisions

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[[Image:2eqy.jpg|left|200px]]


{{Structure
==Solution structure of the ARID domain of Jarid1b protein==
|PDB= 2eqy |SIZE=350|CAPTION= <scene name='initialview01'>2eqy</scene>
<StructureSection load='2eqy' size='340' side='right'caption='[[2eqy]]' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[2eqy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EQY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EQY FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
|GENE= Jarid1b ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eqy OCA], [https://pdbe.org/2eqy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eqy RCSB], [https://www.ebi.ac.uk/pdbsum/2eqy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eqy ProSAT], [https://www.topsan.org/Proteins/RSGI/2eqy TOPSAN]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2eqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eqy OCA], [http://www.ebi.ac.uk/pdbsum/2eqy PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2eqy RCSB]</span>
[https://www.uniprot.org/uniprot/KDM5B_MOUSE KDM5B_MOUSE] Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9.<ref>PMID:17320160</ref> <ref>PMID:17310255</ref>
}}
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eq/2eqy_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2eqy ConSurf].
<div style="clear:both"></div>


'''Solution structure of the ARID domain of Jarid1b protein'''
==See Also==
 
*[[Lysine-specific histone demethylase 3D structures|Lysine-specific histone demethylase 3D structures]]
 
== References ==
==About this Structure==
<references/>
2EQY is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EQY OCA].
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Single protein]]
[[Category: Inoue M]]
[[Category: Inoue, M.]]
[[Category: Kigawa T]]
[[Category: Kigawa, T.]]
[[Category: Muto Y]]
[[Category: Muto, Y.]]
[[Category: Shirouzu M]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Suzuki S]]
[[Category: Shirouzu, M.]]
[[Category: Tanabe W]]
[[Category: Suzuki, S.]]
[[Category: Terada T]]
[[Category: Tanabe, W.]]
[[Category: Yokoyama S]]
[[Category: Terada, T.]]
[[Category: Yokoyama, S.]]
[[Category: arid domain]]
[[Category: dna binding protein]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:52:40 2008''

Latest revision as of 18:55, 29 May 2024

Solution structure of the ARID domain of Jarid1b protein

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